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The impact of dupilumab treatment on SARS-CoV-2 T cell responses in atopic dermatitis patients.度普利尤单抗治疗对特应性皮炎患者严重急性呼吸综合征冠状病毒2(SARS-CoV-2)T细胞反应的影响。
Allergy. 2023 Feb;78(2):571-574. doi: 10.1111/all.15540. Epub 2022 Oct 17.
2
Dupilumab treatment for severe atopic dermatitis in children and SARS-CoV-2 infection: A combination of triggers for psoriasis.度普利尤单抗治疗儿童重度特应性皮炎与SARS-CoV-2感染:银屑病的多种诱发因素组合
J Eur Acad Dermatol Venereol. 2023 May;37(5):e568-e569. doi: 10.1111/jdv.18864. Epub 2023 Jan 21.
3
Atopic dermatitis in adolescents: Effectiveness and safety of dupilumab in a 16-week real-life experience during the COVID-19 pandemic in Italy.青少年特应性皮炎:在意大利新冠疫情期间16周真实临床实践中使用度普利尤单抗的有效性和安全性
Dermatol Ther. 2021 Sep;34(5):e15035. doi: 10.1111/dth.15035. Epub 2021 Jun 25.
4
The impact of dupilumab treatment on severe acute respiratory syndrome coronavirus 2-coronavirus disease 2019 antibody responses in patients with atopic dermatitis.度普利尤单抗治疗对特应性皮炎患者严重急性呼吸综合征冠状病毒2-冠状病毒病2019抗体反应的影响。
Ann Allergy Asthma Immunol. 2022 Jun;128(6):734-736. doi: 10.1016/j.anai.2022.03.019. Epub 2022 Mar 26.
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Facial dermatoses and use of protective mask during Covid-19 pandemic: A clinical and psychological evaluation in patients affected by moderate-severe atopic dermatitis under treatment with dupilumab.在 COVID-19 大流行期间,面部皮肤病和使用防护口罩:接受度普利尤单抗治疗的中重度特应性皮炎患者的临床和心理评估。
Dermatol Ther. 2022 Jul;35(7):e15573. doi: 10.1111/dth.15573. Epub 2022 May 22.
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COVID-19 Symptoms Are Attenuated in Moderate-to-Severe Atopic Dermatitis Patients Treated with Dupilumab.度普利尤单抗治疗中重度特应性皮炎患者的 COVID-19 症状减轻。
J Allergy Clin Immunol Pract. 2022 Jan;10(1):134-142. doi: 10.1016/j.jaip.2021.10.050. Epub 2021 Nov 1.
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Risk of COVID-19 and its complications in patients with atopic dermatitis undergoing dupilumab treatment-a population-based cohort study.患有特应性皮炎并接受度普利尤单抗治疗的患者罹患 COVID-19 及其并发症的风险:一项基于人群的队列研究。
Immunol Res. 2022 Feb;70(1):106-113. doi: 10.1007/s12026-021-09234-z. Epub 2021 Oct 13.
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COVID-19 Does Not Influence the Time to Relapse Following Dupilumab Discontinuation in Patients With Moderate-to-Severe Atopic Dermatitis.新冠病毒不影响中度至重度特应性皮炎患者停用度普利尤单抗后的复发时间。
Dermatitis. 2024 Sep-Oct;35(5):523-524. doi: 10.1089/derm.2023.0304. Epub 2023 Dec 29.
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Early and Long-Term Effects of Dupilumab Treatment on Circulating T-Cell Functions in Patients with Moderate-to-Severe Atopic Dermatitis.度普利尤单抗治疗中重度特应性皮炎患者对循环 T 细胞功能的早期和长期影响。
J Invest Dermatol. 2021 Aug;141(8):1943-1953.e13. doi: 10.1016/j.jid.2021.01.022. Epub 2021 Feb 18.
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Evaluation of adult patients with atopic dermatitis treated with dupilumab: A single-center real-life experience.成人特应性皮炎患者接受度普利尤单抗治疗的评估:一项单中心真实世界经验。
J Cosmet Dermatol. 2022 Oct;21(10):4781-4787. doi: 10.1111/jocd.14785. Epub 2022 Jan 30.

引用本文的文献

1
Exosome-Based Therapeutics in Dermatology.基于外泌体的皮肤病治疗方法
Biomater Res. 2025 May 9;29:0148. doi: 10.34133/bmr.0148. eCollection 2025.
2
A systematic review and expert Delphi Consensus recommendation on the use of vaccines in patients receiving dupilumab: A position paper of the American College of Allergy, Asthma and Immunology.接受度普利尤单抗治疗的患者使用疫苗的系统评价和专家 Delphi 共识推荐:美国过敏、哮喘和免疫学学会的立场文件。
Ann Allergy Asthma Immunol. 2024 Sep;133(3):286-294. doi: 10.1016/j.anai.2024.05.014. Epub 2024 Jun 5.
3
Ally, adversary, or arbitrator? The context-dependent role of eosinophils in vaccination for respiratory viruses and subsequent breakthrough infections.盟友、对手还是仲裁者?嗜酸性粒细胞在呼吸道病毒疫苗接种及其随后突破性感染中的上下文相关作用。
J Leukoc Biol. 2024 Jul 25;116(2):224-243. doi: 10.1093/jleuko/qiae010.

The impact of dupilumab treatment on SARS-CoV-2 T cell responses in atopic dermatitis patients.

作者信息

Ungar Benjamin, Hartzell Susan, Lozano-Ojalvo Daniel, Ghalili Sabrina, Bose Swaroop, Golant Alexandra K, Tan Kathryn, Estrada Yeriel D, Singer Giselle K, Pavel Ana B, Cravedi Paolo, Guttman-Yassky Emma

机构信息

Department of Dermatology and Laboratory of Inflammatory Skin Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

Allergy. 2023 Feb;78(2):571-574. doi: 10.1111/all.15540. Epub 2022 Oct 17.

DOI:10.1111/all.15540
PMID:36181718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9537998/
Abstract
摘要