钩端螺旋体病所致急性肾衰竭——一项为期12年的调查

Acute renal failure in leptospirosis--a 12-year survey.

作者信息

Drinovec J, Kandus A, Bren A F, Sinigoj M, Erzen I, Lĭcina A, Kveder R, Ponokvar R, Mocivnik M, Benedik M

出版信息

Adv Exp Med Biol. 1987;212:265-71. doi: 10.1007/978-1-4684-8240-9_33.

Abstract

From the beginning of 1974 to the end of 1985 141 persons in Slovenia (population 1.9 million) contracted leptospirosis 49 patients were 50 years old or more. All the patients have survived. 8 male patients aged from 18 to 44 had more severe acute renal failure (ARF), 5 of whom were treated with hemodialysis. The authors found that this 100% survival rate did not agree with the findings of many other researches which quote a relatively high mortality rate among older patients. In all 8 patients kidney function was good 1 year or more after ARF. The authors consider that the survival of patients with ARF depends on early and appropriate supportive treatment, which also includes intensive hemodialysis.

摘要

从1974年初到1985年底，斯洛文尼亚（人口190万）有141人感染钩端螺旋体病，其中49名患者年龄在50岁及以上。所有患者均存活。8名年龄在18至44岁的男性患者出现了更严重的急性肾衰竭（ARF），其中5人接受了血液透析治疗。作者发现，这100%的存活率与许多其他研究的结果不一致，那些研究表明老年患者的死亡率相对较高。在所有8名患者中，急性肾衰竭发生1年或更长时间后肾功能良好。作者认为，急性肾衰竭患者的存活取决于早期和适当的支持治疗，其中也包括强化血液透析。