Kennedy N D, Pusey C D, Rainford D J, Higginson A
Postgrad Med J. 1979 Mar;55(641):176-9. doi: 10.1136/pgmj.55.641.176.
About 50 cases of leptospirosis are diagnosed each year in the United Kingdom, with an overall mortality of 5%. Renal failure, in association with jaundice, is commonly held responsible for this figure. Over a period of 18 years, 6 cases of leptospirosis complicated by renal failure were treated at the Royal Air Force Renal Unit; there were 4 survivors. The 2 deaths occurred before the unit policy of daily haemodialysis and total parenteral nutrition, and were both from haemorrhagic complications. The authors believe that patients with leptospirosis and progressive renal impairment should be managed in renal units experienced in the management of the hypercatabolic patient, and that this should improve their prognosis.
在英国,每年约有50例钩端螺旋体病被确诊,总死亡率为5%。肾衰竭合并黄疸通常是导致这一死亡率的原因。在18年的时间里,皇家空军肾脏科治疗了6例并发肾衰竭的钩端螺旋体病患者;其中4例存活。2例死亡发生在该科室实行每日血液透析和全胃肠外营养政策之前,均死于出血并发症。作者认为,患有钩端螺旋体病且有进行性肾功能损害的患者应由有治疗高分解代谢患者经验的肾脏科进行管理,这样应能改善他们的预后。