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钩端螺旋体病与急性肾衰竭——临床经验及文献综述

Leptospirosis and acute renal failure--clinical experiences and a review of the literature.

作者信息

Kennedy N D, Pusey C D, Rainford D J, Higginson A

出版信息

Postgrad Med J. 1979 Mar;55(641):176-9. doi: 10.1136/pgmj.55.641.176.

Abstract

About 50 cases of leptospirosis are diagnosed each year in the United Kingdom, with an overall mortality of 5%. Renal failure, in association with jaundice, is commonly held responsible for this figure. Over a period of 18 years, 6 cases of leptospirosis complicated by renal failure were treated at the Royal Air Force Renal Unit; there were 4 survivors. The 2 deaths occurred before the unit policy of daily haemodialysis and total parenteral nutrition, and were both from haemorrhagic complications. The authors believe that patients with leptospirosis and progressive renal impairment should be managed in renal units experienced in the management of the hypercatabolic patient, and that this should improve their prognosis.

摘要

在英国,每年约有50例钩端螺旋体病被确诊,总死亡率为5%。肾衰竭合并黄疸通常是导致这一死亡率的原因。在18年的时间里,皇家空军肾脏科治疗了6例并发肾衰竭的钩端螺旋体病患者;其中4例存活。2例死亡发生在该科室实行每日血液透析和全胃肠外营养政策之前,均死于出血并发症。作者认为,患有钩端螺旋体病且有进行性肾功能损害的患者应由有治疗高分解代谢患者经验的肾脏科进行管理,这样应能改善他们的预后。

相似文献

6
Acute renal failure in leptospirosis.钩端螺旋体病所致急性肾衰竭
Ir J Med Sci. 1981 Jun;150(6):187-9. doi: 10.1007/BF02938231.
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Acute renal failure in severe leptospirosis.重症钩端螺旋体病所致急性肾衰竭
Nephrol Dial Transplant. 2003 Jun;18(6):1235-6. doi: 10.1093/ndt/gfg110.
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Peritoneal dialysis in hypercatabolic acute renal failure.高分解代谢型急性肾衰竭的腹膜透析
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本文引用的文献

1
Renal function after leptospirosis.钩端螺旋体病后的肾功能
Br Med J. 1967 Aug 19;3(5563):472-3. doi: 10.1136/bmj.3.5563.472.
4
Renal involvement in human leptospirosis.人类钩端螺旋体病的肾脏受累情况。
Br Med J. 1968 Jun 15;2(5606):656-8. doi: 10.1136/bmj.2.5606.656.
5
Leptospirosis. I.钩端螺旋体病。一。
Trans R Soc Trop Med Hyg. 1967;61(6):842-55. doi: 10.1016/0035-9203(67)90045-4.
6
Renal failure in leptospirosis.钩端螺旋体病中的肾衰竭
South Med J. 1970 May;63(5):580-3. doi: 10.1097/00007611-197005000-00022.
7
Leptospirosis in the United States.美国的钩端螺旋体病。
N Engl J Med. 1965 Oct 14;273(16):857-64 contd. doi: 10.1056/NEJM196510142731606.
9
The kidney in human leptospirosis.人类钩端螺旋体病中的肾脏。
Am J Med. 1970 Dec;49(6):780-8. doi: 10.1016/s0002-9343(70)80059-6.
10
Peritoneal dialysis in hypercatabolic acute renal failure.高分解代谢型急性肾衰竭的腹膜透析
Lancet. 1967 Jun 17;1(7503):1331-2. doi: 10.1016/s0140-6736(67)91634-0.

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