Bunker V W, Hinks L J, Stansfield M F, Lawson M S, Clayton B E
Am J Clin Nutr. 1987 Aug;46(2):353-9. doi: 10.1093/ajcn/46.2.353.
Five-day metabolic balance studies for zinc and copper were carried out in 20 housebound elderly people with stable chronic diseases. Subjects were age 70.0-85.1 y, lived in their own homes, and ate self-selected diets. Mean daily intakes for Zn and Cu were 90 mumol and 13.4 mumol with mean negative balances of -16 and -1.1 mumol, respectively. Both balance values significantly differed from equilibrium (p less than 0.05). For Zn and Cu, respectively, mean concentrations were 11.3 and 22.1 mumol/L plasma, 103 and 19.4 mumol/L whole blood, and 98 and 8.7 pmol/10(6) leukocytes. The results for Zn and Cu balance and leukocyte concentrations were different from those obtained by us for healthy elderly people (Am J Clin Nutr 1984;40: 1096-120). A highly significant (r = 0.75, p less than 0.001) correlation was observed between zinc balance and leukocyte zinc concentrations.
对20名患有稳定慢性病的居家老年人进行了为期五天的锌和铜代谢平衡研究。研究对象年龄在70.0至85.1岁之间，居住在自己家中，饮食为自选饮食。锌和铜的平均每日摄入量分别为90微摩尔和13.4微摩尔，平均负平衡分别为-16微摩尔和-1.1微摩尔。两个平衡值均与平衡状态有显著差异（p<0.05）。锌和铜的平均浓度分别为：血浆中11.3微摩尔/升和22.1微摩尔/升，全血中103微摩尔/升和19.4微摩尔/升，白细胞中98皮摩尔/10⁶和8.7皮摩尔/10⁶。锌和铜平衡以及白细胞浓度的结果与我们对健康老年人的研究结果不同（《美国临床营养学杂志》1984年；40：1096 - 120）。锌平衡与白细胞锌浓度之间观察到高度显著的相关性（r = 0.75，p<0.001）。
