Patil Aniket, Kumar Sunil, Inamdar Anil, Acharya Sourya, Wanjari Anil, Bawankule Shilpa, Agrawal Sachin, Sontakke Tushar
Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Science (Deemed to be University) Sawangi Meghe, Wardha, Maharashtra, India.
J Lab Physicians. 2021 Sep 8;14(1):1-5. doi: 10.1055/s-0041-1734015. eCollection 2022 Mar.
Prompt recognition and aggressive management of acute intoxication due to organophosphorus poisoning are essential to minimize the morbidity and mortality. The present study was undertaken to know the prognosis and outcome of organophosphorus poisoning patients with the estimation of low-cost enzymes like the serum amylase level in a population with financial constraints. In this cross-sectional study, we had enrolled 100 cases that had a history of exposure to organophosphorus compounds, and the serum amylase level was measured in all the patients. We assessed the outcome of all the patients in the form of discharge, need of ventilators, intensive care unit stay, and death. The mean serum amylase level in discharge patients was 335.40 ± 192.45, and in the patients who died it was 843.37 ± 22.60. It was significant to predict the outcome ( -value 7.07, -value 0.0001, statistically significant). Serum amylase level shows significant correlation with clinical outcomes in organophosphorus poisoning.
及时识别并积极处理有机磷中毒导致的急性中毒对于降低发病率和死亡率至关重要。本研究旨在了解在经济条件有限的人群中，通过检测血清淀粉酶水平等低成本酶类来评估有机磷中毒患者的预后和结局。
在这项横断面研究中，我们纳入了100例有有机磷化合物接触史的病例，并对所有患者检测了血清淀粉酶水平。我们以出院情况、是否需要呼吸机、重症监护病房住院时间和死亡情况来评估所有患者的结局。
出院患者的血清淀粉酶平均水平为335.40±192.45，死亡患者的血清淀粉酶平均水平为843.37±22.60。预测结局具有显著意义（t值7.07，p值0.0001，具有统计学显著性）。
血清淀粉酶水平与有机磷中毒的临床结局显著相关。
