Chen Yuqin, Zhong Bihua, Jiang Qian, Chen Yilin, He Wenjun, Lai Ning, Zhou Dansha, He Jiahao, Yao Yiting, Shen Yi, Li Juan, Yang Jianuo, Zhang Zhe, Ma Ran, Wang Jian, Liu Chunli
State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University Guangzhou China.
Department of Respiratory and Critical Care Medicine The Second People's Hospital of Foshan (Affiliated Foshan Hospital of Southern Medical University) Foshan Guangdong China.
Pulm Circ. 2022 Jul 1;12(3):e12130. doi: 10.1002/pul2.12130. eCollection 2022 Jul.
The Coronavirus disease 2019 (COVID-19) pandemic has severely affected the lives of people around the world, especially some patients with severe chronic diseases. This study aims to evaluate the impact of the COVID-19 outbreak from December 2019 to April 2020 on treating patients with PH. A questionnaire regarding the medical condition of PH patients during the COVID-19 pandemic was designed by PH diagnostic experts in The First Affiliated Hospital of Guangzhou Medical University, China Respiratory Center. One hundred and fifty-six subjects with PH from non-Hubei regions in China were invited to participate in this survey online. 63.4% ( = 99) of them had difficulty seeing a doctor, and the main reason was fear of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the hospital. Medical treatment was affected in 25% ( = 39) of patients, and who lived in rural areas, and discontinued medical therapy for financial reasons were at a higher risk of medical treatment being affected. Patients who reduced nutrition, and had difficulty seeing a doctor were more likely to get deteriorated. During the epidemic, the hospitalization rate of PH patients was 33.33%. Patients with aggravated PH had a high risk of hospitalization (odds ratio [OR] = 2.844), while patients who visited a doctor during the epidemic reduced the risk of hospitalization (OR = 0.33). In conclusion, during the COVID-19 pandemic, PH patients had difficulty seeing a doctor, and their medical treatment was affected, even worsened, and increased the risk of hospitalization.
2019年冠状病毒病(COVID-19)大流行严重影响了世界各地人们的生活,尤其是一些患有严重慢性病的患者。本研究旨在评估2019年12月至2020年4月COVID-19疫情对肺动脉高压(PH)患者治疗的影响。中国呼吸中心广州医科大学附属第一医院的PH诊断专家设计了一份关于COVID-19大流行期间PH患者病情的调查问卷。邀请了156名来自中国非湖北地区的PH患者在线参与这项调查。其中63.4%(n = 99)的患者就医困难,主要原因是担心在医院感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)。25%(n = 39)的患者治疗受到影响,这些患者居住在农村地区,因经济原因中断治疗的患者治疗受影响的风险更高。营养减少且就医困难的患者病情更易恶化。疫情期间,PH患者的住院率为33.33%。PH病情加重的患者住院风险较高(优势比[OR]=2.844),而在疫情期间就医的患者住院风险降低(OR = 0.33)。总之,在COVID-19大流行期间,PH患者就医困难,其治疗受到影响,甚至恶化,并增加了住院风险。