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血清铁蛋白和维生素B12缺乏而非叶酸缺乏,在居住于德里贫民窟的青春期女孩中很常见。

Deficiencies of Serum Ferritin and Vitamin B12, but not Folate, are Common in Adolescent Girls Residing in a Slum in Delhi.

作者信息

Gupta Bansal Priyanka, Singh Toteja Gurudayal, Bhatia Neena, Kishore Vikram Naval, Siddhu Anupa, Kumar Garg Ashok, Kumar Roy Ashok

机构信息

1 Centre for Promotion of Nutrition Research and Training with Special Focus on North-East, Tribal and Inaccessible Population (Indian Council of Medical Research), New Delhi, India.

2 Department of Food & Nutrition, Lady Irwin College, University of Delhi, New Delhi, India.

出版信息

Int J Vitam Nutr Res. 2015;85(1-2):14-22. doi: 10.1024/0300-9831/a000219.

Abstract

Anemia among adolescent girls is one of the major challenges faced by India. The present study was undertaken to assess the prevalence of anemia and status of other hematological parameters among adolescent girls (11 - 18 years) residing in an urban slum of Delhi. A total of 794 adolescent girls were recruited for the study. The prevalence of anemia was estimated using the cyanmethemoglobin method. Serum levels of ferritin, folic acid and vitamin B12 were estimated for anemic subjects. The prevalence of anemia was reported as 58.7 %, with 31.6 %, 25.7 % and 1.4 % of subjects being mild, moderate and severely anemic. Hemoglobin levels of subjects who had attained menarche were found to be significantly lower than those who had not attained menarche. The prevalence of serum ferritin, folic acid and vitamin B12 deficiency among those who were anemic was reported as 41.1 %, 5.0 % and 63.3 % respectively. A total of 23.5 % anemic subjects had concomitant micronutrient deficiencies of serum vitamin B12 and ferritin. The results indicate that supplemental iron and vitamin B12 may better address the burden of anemia in adolescent girls in Delhi.

摘要

青春期女孩贫血是印度面临的主要挑战之一。本研究旨在评估居住在德里一个城市贫民窟的青春期女孩(11 - 18岁)贫血的患病率以及其他血液学参数状况。总共招募了794名青春期女孩参与该研究。采用氰化高铁血红蛋白法估算贫血患病率。对贫血受试者测定血清铁蛋白、叶酸和维生素B12水平。报告的贫血患病率为58.7%,其中轻度、中度和重度贫血的受试者分别占31.6%、25.7%和1.4%。已初潮的受试者血红蛋白水平显著低于未初潮的受试者。报告显示,贫血者中血清铁蛋白、叶酸和维生素B12缺乏的患病率分别为41.1%、5.0%和63.3%。共有23.5%的贫血受试者同时存在血清维生素B12和铁蛋白的微量营养素缺乏。结果表明,补充铁和维生素B12可能能更好地应对德里青春期女孩的贫血负担。

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