Dr Nasrin Akter, Lecturer, Department of Physiology, Shaheed Tajuddin Ahmad Medical College, Gazipur, Bangladesh; E-mail:
Mymensingh Med J. 2022 Oct;31(4):920-924.
Patients often present with chronic kidney disease (CKD) complicated with hypocalcaemia. Lower serum calcium is independently associated with chronic kidney disease. Aim of this study was to assess of serum calcium level in chronic kidney diseased patients in order to compare this parameter with healthy subjects. This analytical type of cross-sectional study was carried out in the Physiology department, Mymensingh Medical College, Mymensingh, Bangladesh from July 2018 to June 2019. A total number of 200 subjects, age range 30-70 year were included in this study. Among 200 subjects, 100 healthy were taken as control group (Group I) and 100 chronic kidney diseased patients were taken as study group (Group II). Control group (Group I) subdivided into male healthy subject (Group IA) and female healthy subject (Group IB). Also study group (Group II) subdivided into male chronic kidney diseased patient (Group IIA) and female chronic kidney diseased patient (Group IIB). The results were calculated and analyzed by using SPSS version-21. Expression of data as mean±SE and statistical significance of difference among the group was calculated by unpaired student's 't' test. In this study we found that mean±SE serum calcium of Group IA and Group IIA were 9.60±0.09mg/dl & 8.04±0.03mg/dl respectively. The mean±SE serum calcium of Group IB and Group IIB were 9.38±0.096mg/dl & 8.19±0.05mg/dl respectively. Serum calcium was significantly decreased in study groups in comparison with control groups (p<0.001). By this study we therefore recommended that routine estimation of this parameter is important for prevention of complication related to chronic kidney disease for leading a healthy life.
患者常伴有慢性肾脏病（CKD）合并低钙血症。血清钙降低与慢性肾脏病独立相关。本研究旨在评估慢性肾脏病患者的血清钙水平，以便将该参数与健康受试者进行比较。这是一项在孟加拉国迈门辛医科大学生理学系进行的分析性横断面研究，时间为 2018 年 7 月至 2019 年 6 月。本研究共纳入 200 名年龄在 30-70 岁的受试者。在 200 名受试者中，选择 100 名健康者作为对照组（I 组），100 名慢性肾脏病患者作为研究组（II 组）。对照组（I 组）分为男性健康受试者（IA 组）和女性健康受试者（IB 组）。同样，研究组（II 组）分为男性慢性肾脏病患者（IIA 组）和女性慢性肾脏病患者（IIB 组）。结果采用 SPSS 版本 21 进行计算和分析。数据表示为均数±标准误，组间差异的统计学意义采用非配对学生 t 检验进行计算。在这项研究中，我们发现 IA 组和 IIA 组的血清钙均值±标准误分别为 9.60±0.09mg/dl 和 8.04±0.03mg/dl。IB 组和 IIB 组的血清钙均值±标准误分别为 9.38±0.096mg/dl 和 8.19±0.05mg/dl。与对照组相比，研究组的血清钙显著降低（p<0.001）。因此，通过这项研究，我们建议常规估计该参数对于预防与慢性肾脏病相关的并发症、过上健康的生活是很重要的。
