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化妆品中甘油三酯的修订安全性评估。

Amended Safety Assessment of Triglycerides as Used in Cosmetics.

作者信息

Fiume Monice M, Bergfeld Wilma F, Belsito Donald V, Hill Ronald A, Klaassen Curtis D, Liebler Daniel C, Marks James G, Shank Ronald C, Slaga Thomas J, Snyder Paul W, Heldreth Bart

机构信息

44002Cosmetic Ingredient Review Senior Director.

Expert Panel for Cosmetic Ingredient Safety Member.

出版信息

Int J Toxicol. 2022 Dec;41(3_suppl):22-68. doi: 10.1177/10915818221123790. Epub 2022 Oct 2.

DOI:10.1177/10915818221123790
PMID:36189772
Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 51 triglycerides; 25 of these ingredients were previously reviewed by the Panel, and 26 are reviewed herein for the first time. The majority of the ingredients named in this assessment have several functions, with most reported to function as skin conditioning agents (occlusive or emollient) and/or viscosity increasing agents in cosmetics; some are also reported to function as a fragrance or solvent. The Panel reviewed relevant new data, including frequency and concentration of use, and considered the data from previous reports. The Panel concluded the 51 triglycerides reviewed in this report are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

摘要

化妆品成分安全专家小组(小组)评估了51种甘油三酯的安全性;其中25种成分此前已由小组进行过审查,另有26种在此首次进行审查。本次评估中提到的大多数成分具有多种功能,大多数报告称在化妆品中起皮肤调理剂(封闭性或润肤性)和/或增稠剂的作用;有些还报告称起香料或溶剂的作用。小组审查了相关新数据,包括使用频率和浓度,并参考了以往报告中的数据。小组得出结论,本报告中审查的51种甘油三酯在本安全评估所述的当前使用方法和浓度下用于化妆品是安全的。

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