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COVID-19 是否导致感音神经性听力下降?一项 COVID-19 前后听力评估研究。

Is COVID-19 to Blame for Sensorineural Hearing Deterioration? A Pre/Post COVID-19 Hearing Evaluation Study.

机构信息

Department of Communication Disorders, Ariel University, Ariel, Israel.

Meuhedet Health Services, Tel Aviv, Israel.

出版信息

Laryngoscope. 2023 Aug;133(8):1976-1981. doi: 10.1002/lary.30400. Epub 2022 Oct 3.

DOI:10.1002/lary.30400
PMID:36189952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9874895/
Abstract

OBJECTIVES

Here, we aimed to (a) determine whether a clinically significant sensorineural hearing loss (SNHL) change could be detected in post-coronavirus disease (COVID-19) hearing levels on comparing them with pre-infection hearing levels after controlling for the effect of age and (b) to identify risk factors, such as hypertension, diabetes, and smoking, which increase the likelihood of hearing loss in COVID-19 patients.

METHODS

We retrospectively analyzed hearing thresholds in unvaccinated patient's pre- and post-COVID-19 infection. Thresholds were controlled for age and the duration between the pre- and post-COVID-19 hearing evaluations. Correlations between additional COVID-19-related symptoms, hypertension, diabetes, and smoking and hearing threshold changes were analyzed.

RESULTS

A significant (but not clinical) threshold elevation was found post-COVID-19 infection. However, on controlling for age and the duration between the pre- and post-COVID-19 hearing evaluations, no significant threshold elevation was found. No significant correlation was found between hearing threshold changes and additional COVID-19-related symptoms, hypertension, diabetes, or smoking.

CONCLUSION

COVID-19 did not lead to a significant hearing threshold elevation in our cohort, even among patients with additional COVID-19 symptoms, hypertension, or diabetes mellitus or among those who smoked.

LEVEL OF EVIDENCE

3: nonrandomized controlled cohort, follow-up study Laryngoscope, 133:1976-1981, 2023.

摘要

目的

本研究旨在(a)确定在控制年龄因素后,比较感染新冠病毒前后的听力水平,是否能检测到新冠病毒后出现的临床显著感音神经性听力损失(SNHL)变化;以及(b)确定高血压、糖尿病和吸烟等增加新冠病毒患者听力损失风险的因素。

方法

我们对未接种疫苗的患者感染新冠病毒前后的听力阈值进行了回顾性分析。阈值控制在年龄和新冠病毒前后听力评估之间的时间间隔。分析了与新冠病毒相关的其他症状、高血压、糖尿病和吸烟与听力阈值变化之间的相关性。

结果

在感染新冠病毒后,发现阈值有显著(但无临床意义)的升高。然而,在控制年龄和新冠病毒前后听力评估之间的时间间隔后,未发现显著的阈值升高。听力阈值变化与新冠病毒相关的其他症状、高血压、糖尿病或吸烟之间没有显著相关性。

结论

在我们的队列中,新冠病毒并未导致显著的听力阈值升高,即使在有其他新冠病毒症状、高血压或糖尿病或吸烟的患者中也是如此。

证据等级

3:非随机对照队列,随访研究《喉镜》,133:1976-1981,2023。

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引用本文的文献

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Front Neurol. 2023 May 18;14:1172441. doi: 10.3389/fneur.2023.1172441. eCollection 2023.