Hartmann J F, Beaufils F, Vervel C
Arch Fr Pediatr. 1987 Jun-Jul;44(6):423-31.
The annual incidence of bronchopulmonary dysplasia (BPD) is presently 1.3 case p. 1,000 alive births. The most severe forms of BPD are characterized by a prolonged oxygen-dependence and a spontaneous evolution marked by numerous complications which could be life-threatening. We studied retrospectively 65 premature infants with BPD who underwent ventilation for one month or more during the first weeks of life. Comparison between survivors and children deceased during the first year of life allowed for discerning 5 prognostic criteria: the nature and severity of initial respiratory disease, the respiratory improvement during the first trimester, the results of hematosis by age 3 months, the ability of maintaining and increasing the respiratory improvement while reducing the therapeutic management, the weight and head circumference gains. The respective parts and conditions of oxygen therapy and prolonged mechanical ventilation in severe cases of BPD are discussed.
支气管肺发育不良（BPD）目前的年发病率为每1000例活产中有1.3例。最严重形式的BPD的特点是长期依赖氧气，且自然病程中伴有众多可能危及生命的并发症。我们回顾性研究了65例患有BPD的早产儿，这些患儿在出生后的头几周内接受了一个月或更长时间的通气治疗。通过比较存活者与一岁内死亡的患儿，识别出5个预后标准：初始呼吸系统疾病的性质和严重程度、孕早期的呼吸改善情况、3个月龄时的血液学指标结果、在减少治疗措施的同时维持并增强呼吸改善的能力、体重和头围增长情况。文中还讨论了在严重BPD病例中氧疗和延长机械通气各自的作用及条件。
