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溃疡性结肠炎发作时的单核细胞增生李斯特菌败血症

Listeria Monocytogenes Septicemia in the Setting of an Ulcerative Colitis Flare.

作者信息

Seraphin Michael J, Isern Raul, Maclean Alyssa K, Heli Christopher M, Shaw Michael B

机构信息

Division of Infectious Disease, Creighton University School of Medicine, Omaha, USA.

Department of Internal Medicine, Creighton University School of Medicine, Omaha, USA.

出版信息

Cureus. 2022 Aug 31;14(8):e28638. doi: 10.7759/cureus.28638. eCollection 2022 Aug.

Abstract

A 51-year-old patient with a history of ulcerative colitis was admitted after three days of bloody diarrhea and abdominal pain. The patient had been trialing different immunosuppressive therapies over the past year. An acute flare of ulcerative colitis was confirmed, and our patient began to improve upon IV methylprednisolone. Blood cultures on admission were positive for . IV ampicillin and gentamicin were begun for treatment. Upon discharge, the patient was switched to high-dose amoxicillin. This case report shows that can be a cause of septicemia in ulcerative colitis patients undergoing immunosuppressive therapy.

摘要

一名有溃疡性结肠炎病史的51岁患者,在出现血性腹泻和腹痛三天后入院。该患者在过去一年中一直在试用不同的免疫抑制疗法。溃疡性结肠炎急性发作得到确诊,我们的患者在静脉注射甲泼尼龙后开始好转。入院时血培养结果为 阳性。开始静脉注射氨苄青霉素和庆大霉素进行治疗。出院时,患者改用高剂量阿莫西林。本病例报告表明, 在接受免疫抑制治疗的溃疡性结肠炎患者中可能是败血症的一个病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9703/9524853/67fcf992f92b/cureus-0014-00000028638-i01.jpg

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Diagnosis and classification of ulcerative colitis.溃疡性结肠炎的诊断与分类。
Autoimmun Rev. 2014 Apr-May;13(4-5):463-6. doi: 10.1016/j.autrev.2014.01.028. Epub 2014 Jan 11.

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