Respiratory Disease Center, Fukujuji Hospital, Japan Anti-tuberculosis Association, Kiyose City, Tokyo, Japan.
Respiratory Care and Rehabilitation Center, Fukujyuji Hospital, Japan Anti-tuberculosis Association, Kiyose City, Tokyo, Japan.
Medicine (Baltimore). 2022 Sep 23;101(38):e30704. doi: 10.1097/MD.0000000000030704.
The loss of muscle mass and changes in muscle composition are important factors for assessing skeletal muscle dysfunction. The cross-sectional area (CSA) of muscle is usually used to assess skeletal muscle function. However, the CSA of skeletal muscle can be difficult for clinicians to measure because a specific 3D image analysis system for computed tomography (CT) scans is needed. Therefore, we conducted a study to develop a new method of easily assessing physical activity, in which the thickness of the erector spinae muscles (ESMT) was measured by CT, and to compare ESMT to the CSA of the erector spinae muscles (ESMCSA) in patients with nontuberculous mycobacteria (NTM) pulmonary infections who underwent surgery after some preoperative examinations, such as laboratory tests, chest CT scans, spirometry, and 6-minute walk tests (6MWT). We retrospectively studied adult patients with NTM pulmonary infections who underwent a lobectomy at Fukujuji Hospital from April 2010 to March 2016. We assessed the correlations between ESMT and different variables, including ESMCSA. Sixty-one patients with NTM pulmonary infections were included. The median ESMT and ESMCSA were 1371 mm2 (IQR 1178-1784 mm2) and 28.5 mm (IQR 25.4-31.7 mm), respectively, and a very strong linear correlation was observed between ESMT and ESMCSA (R = 0.858, P < .001). ESMT and ESMCSA were positively associated with body weight (ESMT: R = 0.540, P < .001, ESMCSA: R = 0.714, P < .001), body mass index (ESMT: R = 0.421, P < .001, ESMCSA: R = 0.560, P < .001), the 6MWT value (ESMT: R = 0.413, P = .040, ESMCSA: R = 0.503, P = .010), vital capacity (ESMT: R = 0.527, P < .001, ESMCSA: R = 0.577, P < .001), and the forced expiratory volume in 1 second (ESMT: R = 0.460, P < .001, ESMCSA: R = 0.532, P < .001). We demonstrated that compared to ESMCSA, ESMT is easily measured by CT and can be a useful parameter for clinically evaluating physical activity. Furthermore, ESMT and ESMCSA were related to physical activity, as measured by the 6MWT and spirometry.
肌肉质量的损失和肌肉成分的变化是评估骨骼肌功能的重要因素。肌肉的横截面积 (CSA) 通常用于评估骨骼肌功能。然而，临床医生很难测量骨骼肌 CSA，因为需要特定的 CT 扫描（CT）的三维图像分析系统。因此，我们进行了一项研究，以开发一种新的方法来轻松评估体力活动，通过 CT 测量竖脊肌厚度 (ESMT)，并将 ESMT 与接受非结核分枝杆菌 (NTM) 肺部感染手术的患者的竖脊肌 CSA (ESMCSA) 进行比较术前检查，如实验室检查、胸部 CT 扫描、肺量计和 6 分钟步行测试（6MWT）。我们回顾性研究了 2010 年 4 月至 2016 年 3 月在福珠寺医院接受肺叶切除术的 NTM 肺部感染的成年患者。我们评估了 ESMT 与包括 ESMCSA 在内的不同变量之间的相关性。共纳入 61 例 NTM 肺部感染患者。中位 ESMT 和 ESMCSA 分别为 1371mm2（IQR 1178-1784mm2）和 28.5mm（IQR 25.4-31.7mm），ESMT 和 ESMCSA 之间存在很强的线性相关性（R=0.858，P<0.001）。ESMT 和 ESMCSA 与体重呈正相关（ESMT：R=0.540，P<0.001，ESMCSA：R=0.714，P<0.001）、体重指数（ESMT：R=0.421，P<0.001，ESMCSA：R=0.560，P<0.001）、6MWT 值（ESMT：R=0.413，P=0.040，ESMCSA：R=0.503，P=0.010）、肺活量（ESMT：R=0.527，P<0.001，ESMCSA：R=0.577，P<0.001）和 1 秒用力呼气量（ESMT：R=0.460，P<0.001，ESMCSA：R=0.532，P<0.001）。我们表明，与 ESMCSA 相比，ESMT 可通过 CT 轻松测量，并且可以成为临床评估体力活动的有用参数。此外，ESMT 和 ESMCSA 与 6MWT 和肺量计测量的体力活动有关。
