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梭菌性肌坏死——老年人中一种罕见且诊断不足的病症:一例伴有严重跳跃性病变的病例及治疗指南概述

Clostridium myonecrosis - a rare and underdiagnosed condition in the elderly: a case with severe skipping lesions and an overview of treatment guidelines.

作者信息

Van Asbroeck Ellen, Vasileiadou Ourania, De Laere Sylvie, Van Hedent Eddy, Devue Katleen

机构信息

Department of Surgery, ASZ Aalst, Aalst, Belgium.

Department of Emergency Medicine, ASZ Aalst, Aalst, Belgium.

出版信息

Int J Emerg Med. 2022 Oct 5;15(1):56. doi: 10.1186/s12245-022-00458-w.

DOI:10.1186/s12245-022-00458-w
PMID:36199023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9533516/
Abstract

We present an unusual and severe case of spontaneous clostridial myonecrosis (SCM) in an elderly patient, with severe skipping lesions spread throughout the body. CT imaging, combined with postmortem available blood cultures, confirmed the diagnosis. We noted an underrepresentation of SCM in the cohort of elderly patients (≥ 85 years), upon a review of case reports in the literature over the last decade. Given the worldwide demographic change resulting in an increase in the number of visits to emergency departments for this age group, it is likely that SCM is underdiagnosed in these elderly patients. This case report aims to increase awareness among emergency physicians to recognize the disease as well as to provide a treatment guideline, in order to provide better care and outcome.

摘要

我们报告了一例老年患者发生的罕见且严重的自发性梭菌性肌坏死(SCM)病例,其全身出现严重的跳跃性病变。CT成像结合死后血培养确诊了该诊断。在回顾过去十年的文献病例报告时,我们注意到老年患者(≥85岁)队列中SCM的病例较少。鉴于全球人口结构变化导致该年龄组到急诊科就诊的人数增加,这些老年患者中的SCM很可能未得到充分诊断。本病例报告旨在提高急诊医生对该疾病的认识,并提供治疗指南,以便提供更好的护理和治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/b2f9abea4f10/12245_2022_458_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/0f4c53911402/12245_2022_458_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/7c9a3364be55/12245_2022_458_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/07e4e31c8441/12245_2022_458_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/932601978fec/12245_2022_458_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/b7a15e24b77c/12245_2022_458_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/611adebf642d/12245_2022_458_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/01cb9e3b7eac/12245_2022_458_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/b2f9abea4f10/12245_2022_458_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/0f4c53911402/12245_2022_458_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/7c9a3364be55/12245_2022_458_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/07e4e31c8441/12245_2022_458_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/932601978fec/12245_2022_458_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/b7a15e24b77c/12245_2022_458_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/611adebf642d/12245_2022_458_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/01cb9e3b7eac/12245_2022_458_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0086/9533516/b2f9abea4f10/12245_2022_458_Fig8_HTML.jpg

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2
Spontaneous Non-Traumatic Clostridium perfringens Sepsis.自发性非创伤性产气荚膜梭菌败血症
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Comparative efficacy of antibiotics in treating experimental Clostridium septicum infection.抗生素治疗实验性梭状芽孢杆菌感染的疗效比较。
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Deadly combination: and colorectal malignancy.致命组合:与结肠直肠恶性肿瘤。
BMJ Case Rep. 2017 Dec 2;2017:bcr-2017-222759. doi: 10.1136/bcr-2017-222759.
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Spontaneous Clostridium perfringens myonecrosis: Case report, radiologic findings, and literature review.自发性产气荚膜梭菌性肌坏死:病例报告、影像学表现及文献综述
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