Department of Ultrasound Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
Department of Pathology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, China.
J Healthc Eng. 2022 Sep 26;2022:9336185. doi: 10.1155/2022/9336185. eCollection 2022.
Previous studies suggest that triple-negative breast cancer (TNBC) may have unique imaging characteristics, however, studies focused on the imaging characteristics of TNBC are still limited. The aim of the present study is to analyze the ultrasonic characteristics of TNBC and to provide more reliable information on imaging diagnosis of TNBC. This retrospective study was performed including 162 TNBC patients with 184 TNBC lesions. 174 non-TNBC cases with 196 lesions were used as the control group. The median size of TNBC lesions and non-TNBC lesions were 23 mm × 16 mm and 21 mm × 15 mm, respectively. The shape of most breast cancer lesions was irregular. However, 15.30% (28/183) TNBC lesions and 16.84% (33/196) non-TNBC lesions were oval-shaped. Most breast cancer lesions (79.78% TNBC & 85.71% non-TNBC) were ill-defined. In comparison to non-TNBC, the distinctive ultrasonic characteristics of TNBC were summarized as three features: calcifications, posterior acoustic, and blood flow. Microcalcifications was less common in non-TNBC. The remarkable posterior acoustic characteristics on TNBC were no posterior acoustic features (136, 73.91%). Avascular pattern (21.74%) was also more common in TNBC. The other feature of TNBC was markedly hypoechoic lesions (23.91%). The above-mentioned differences between TNBC and non-TNBC were significant. 93.48% TBNC and 94.39% non-TNBC lesions were in BI-RADS-US category of 4A-5. The results indicate that TNBC has some distinctive ultrasound characteristics. Ultrasound is a useful adjunct in early detection of breast cancer. A combination of ultrasound with mammography is excellent for detecting breast cancer.
先前的研究表明，三阴性乳腺癌（TNBC）可能具有独特的影像学特征，然而，专注于 TNBC 影像学特征的研究仍然有限。本研究旨在分析 TNBC 的超声特征，为 TNBC 的影像学诊断提供更可靠的信息。这是一项回顾性研究，纳入了 162 例 TNBC 患者的 184 个 TNBC 病灶，同时纳入了 196 个病灶的 174 例非 TNBC 病例作为对照组。TNBC 病灶和非 TNBC 病灶的中位大小分别为 23mm×16mm 和 21mm×15mm。大多数乳腺癌病灶的形状不规则，但 15.30%（28/183）的 TNBC 病灶和 16.84%（33/196）的非 TNBC 病灶呈椭圆形。大多数乳腺癌病灶（79.78%的 TNBC 和 85.71%的非 TNBC）边界不清。与非 TNBC 相比，TNBC 的超声特征可总结为三个特征：钙化、后方声影和血流。非 TNBC 中微钙化较少见。TNBC 上显著的后方声影特征是无后方声影特征（136 个，73.91%）。无血管模式（21.74%）也更常见于 TNBC。TNBC 的另一个特征是明显的低回声病灶（23.91%）。这些 TNBC 和非 TNBC 之间的差异具有统计学意义。93.48%的 TNBC 和 94.39%的非 TNBC 病灶在 BI-RADS-US 分类中为 4A-5。结果表明，TNBC 具有一些独特的超声特征。超声是早期发现乳腺癌的有用辅助手段。超声联合乳腺 X 线摄影对于检测乳腺癌具有极好的效果。
