Noushad Shahida, Sahoo Dibyajyoti, Basavarajegowda Abhishekh, Toora Esha, Paudel Purshotam
Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Asian J Transfus Sci. 2022 Jan-Jun;16(1):124-127. doi: 10.4103/ajts.ajts_160_21. Epub 2022 Jul 30.
Priapism is a rare presentation of Chronic Myeloid Leukaemia (CML). It is also considered a medical emergency as delay in treatment may lead to impotence. Prompt medical and surgical interventions such as hydroxyurea, analgesia, phenylephrine injection and aspiration, open surgical shunting, and local radiation therapy are essential. Leukapheresis effectively reduces leukocyte count rapidly and effectively, thereby an important therapy along with other standard of care in CML-induced priapism. In the present case, priapism was the presenting symptom of CML. The same was managed with various modalities such as hydroxyurea, allopurinol, antibiotics, analgesics, sedatives, phenylephrine injection, and aspiration but failed to reduce priapism pain. With a single cycle of leukapheresis, priapism pain could be reduced significantly.
阴茎异常勃起是慢性粒细胞白血病（CML）的一种罕见表现。它也被视为一种医疗急症，因为治疗延迟可能导致阳痿。及时的药物和手术干预，如羟基脲、镇痛、去氧肾上腺素注射和穿刺抽吸、开放性手术分流以及局部放射治疗至关重要。白细胞去除术能迅速有效地降低白细胞计数，因此是治疗CML所致阴茎异常勃起的重要疗法，与其他标准治疗方法一同使用。在本病例中，阴茎异常勃起是CML的首发症状。通过多种方式进行治疗，如羟基脲、别嘌醇、抗生素、镇痛药、镇静剂、去氧肾上腺素注射和穿刺抽吸，但未能减轻阴茎异常勃起的疼痛。经过一个疗程的白细胞去除术，阴茎异常勃起的疼痛得以显著减轻。
