Kamidani Ryo, Chiba Naokazu, Kuroda Ayumi, Uchida Akihiro, Okada Hideshi
Department of Emergency and Disaster Medicine, Gifu University, Gifu, JPN.
Cureus. 2024 May 30;16(5):e61351. doi: 10.7759/cureus.61351. eCollection 2024 May.
Cytoreduction in leukostasis can be achieved using leukapheresis. We report a case of chronic myeloid leukemia (CML) identified by a persistent erection, which was successfully treated using the Spectra Optia®︎ apheresis system. A 29-year-old male presented with an erection for 12 hours without identified triggers and no improvement despite penile corpus cavernosum puncture. His white blood cell count was 458,930/μL. A diagnosis of CML-induced persistent erection with secondary hyperleukocytosis was established. Following an emergency bilateral penile corpus cavernosum incision (distal shunting), he received hydroxyurea and febuxostat. Persistent erection resolved after leukapheresis for two consecutive days. Rapid leukocyte count reduction can effectively address leukostasis in CML without major complications.
使用白细胞单采术可实现白细胞淤滞的细胞数量减少。我们报告一例通过持续性勃起确诊的慢性髓性白血病（CML）病例，该病例使用Spectra Optia®血液成分分离系统成功治愈。一名29岁男性出现勃起达12小时，无明确诱因，尽管进行了阴茎海绵体穿刺仍无改善。他的白细胞计数为458,930/μL。确诊为CML诱发的持续性勃起伴继发性白细胞增多症。在紧急进行双侧阴茎海绵体切开术（远端分流）后，他接受了羟基脲和非布司他治疗。连续两天进行白细胞单采术后，持续性勃起症状消失。快速降低白细胞计数可有效解决CML中的白细胞淤滞问题，且无重大并发症。
