Hall G, Sugden J K, Waghela M B
Arzneimittelforschung. 1987 May;37(5):582-4.
1OH-Pyrrolizino [1,2-b]quinolines exhibited intercalation when tested by the following methods: effect of DNA on spectral properties, spectrophotometric titration, fluorescence enhancement of homidium bromide (ethidium bromide), thermal denaturation of DNA, effect on covalently closed circular double stranded PM-2 (Col E 1 plasmid) DNA. Some of the compounds showed antiproliferative activity in HeLa cells.
1-羟基吡咯并[1,2 - b]喹啉在通过以下方法测试时表现出嵌入作用：DNA对光谱性质的影响、分光光度滴定、溴化乙锭（溴化乙啶）的荧光增强、DNA的热变性、对共价闭合环状双链PM - 2（Col E 1质粒）DNA的影响。一些化合物在HeLa细胞中显示出抗增殖活性。
