A study of drug binding to DNA by partial intercalation using a model phenazine derivative.
作者信息
Kleinwächter V, Balcarová Z, Reinert K E, Triebel H, Grezes J R, Bär H
出版信息
Gen Physiol Biophys. 1986 Aug;5(4):423-32.
PMID:3770461
Abstract
Spectrophotometry, thermal denaturation, sedimentation, and viscometric techniques were used in a study of interaction of double helical DNA with an asymmetric phenazinium derivative, aposafranine. The results obtained indicate that aposafranine binds to DNA by a single binding mode, a wedge-like partial intercalation.
摘要
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