Marcucella H, Munro I
Alcohol Drug Res. 1987;7(5-6):405-14.
The present experiments demonstrated that the within session patterns of ethanol consumption of animals given unrestricted access to both food and water can be controlled by altering the schedule of access to ethanol. The first experiment demonstrated that the number of ethanol responses emitted per bout was inversely related to the number of one hour access periods presented per session. In a second experiment, ethanol access was limited to only the dark period of a 12 hour light-dark cycle. Total daily ethanol responding was similar to that of animals that had access to ethanol 23 hours a day. Further restrictions on ethanol availability by restricting access to the last 20 minutes of each hour of the dark period, resulted in an increase in the number of responses emitted per bout.
目前的实验表明,对于食物和水供应不受限制的动物,通过改变给予乙醇的时间安排,可以控制其在实验期间的乙醇消耗模式。第一个实验表明,每次饮酒发作时发出的乙醇反应次数与每次实验中提供的1小时饮酒时间段数量呈负相关。在第二个实验中,乙醇供应仅限于12小时明暗循环中的黑暗期。每日总的乙醇反应与每天有23小时可获取乙醇的动物相似。通过限制在黑暗期每小时的最后20分钟获取乙醇,进一步限制乙醇的可获得性,导致每次饮酒发作时发出的反应次数增加。