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气相色谱-离子淌度谱法作为一种快速检测室内和环境空气中危险挥发性有机化合物的工具:以大学校园为例的研究。

Gas Chromatography - Ion Mobility Spectrometry as a tool for quick detection of hazardous volatile organic compounds in indoor and ambient air: A university campus case study.

机构信息

Laboratory for Instrumentation, Biomedical Engineering and Radiation Physics (LibPhys-UNL), 119482NOVA School of Science and Technology, NOVA University of Lisbon, Caparica, Portugal.

NMT, S. A., Caparica, Portugal.

出版信息

Eur J Mass Spectrom (Chichester). 2022 Oct;28(5-6):113-126. doi: 10.1177/14690667221130170. Epub 2022 Oct 5.

DOI:10.1177/14690667221130170
PMID:36200142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9647320/
Abstract

Society's concerns about the citizens exposure to possibly dangerous environments have recently risen; nevertheless, the assessment of indoor air quality still represents a major contemporary challenge. The volatile organic compounds (VOCs) are among the main factors responsible for deteriorating air quality conditions. These analytes are very common in daily-use environments and they can be extremely hazardous to human health, even at trace concentrations levels. For these reasons, their quick detection, identification, and quantification are crucial tasks, especially for indoor and heavily-populated scenarios, where the exposure time is usually quite long. In this work, a Gas Chromatography - Ion Mobility Spectrometry (GC-IMS) device was used for continuous monitoring indoor and ambient air environments at a large-scale, due to its outstanding levels of sensibility, selectivity, analytical flexibility, and almost real-time monitoring capability. A total of 496 spectra were collected from 15 locations of a university campus and posteriorly analysed. Overall, 23 compounds were identified among the 31 detected. Some of them, like Ethanol and 2-Propanol, were reported as being very hazardous to the human organism, especially in indoor environments. The achieved results confirmed the suitability of GC-IMS technology for air quality assessment and monitoring of VOCs and, more importantly, proved how dangerous indoor environments can be in scenarios of continuous exposure.

摘要

社会对公民可能暴露于危险环境的担忧最近有所增加;然而,室内空气质量评估仍然是当代的一个重大挑战。挥发性有机化合物(VOCs)是导致空气质量恶化的主要因素之一。这些分析物在日常使用环境中非常常见,即使在痕量浓度水平下,它们也可能对人类健康造成极大危害。出于这些原因,快速检测、识别和定量这些化合物至关重要,尤其是在室内和人口密集的场景中,人们在这些场景中的暴露时间通常相当长。在这项工作中,由于 GC-IMS 设备具有出色的灵敏度、选择性、分析灵活性和几乎实时监测能力,因此被用于对大规模的室内和环境空气进行连续监测。从大学校园的 15 个地点共采集了 496 个光谱,并对其进行了分析。总的来说,在检测到的 31 种化合物中鉴定出了 23 种。其中一些化合物,如乙醇和 2-丙醇,被报道对人体组织非常危险,尤其是在室内环境中。所获得的结果证实了 GC-IMS 技术在评估和监测 VOC 方面的适用性,更重要的是,证明了在持续暴露的情况下,室内环境可能会多么危险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/6706b80b0005/10.1177_14690667221130170-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/2d550f98a704/10.1177_14690667221130170-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/768c14ec6cab/10.1177_14690667221130170-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/ddb8cae8ed2e/10.1177_14690667221130170-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/d40d2fea8599/10.1177_14690667221130170-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/108f49a6dc66/10.1177_14690667221130170-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/66f72675632a/10.1177_14690667221130170-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/4d1413b1aade/10.1177_14690667221130170-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/b457083ba982/10.1177_14690667221130170-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/6706b80b0005/10.1177_14690667221130170-fig9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/2d550f98a704/10.1177_14690667221130170-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/768c14ec6cab/10.1177_14690667221130170-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/ddb8cae8ed2e/10.1177_14690667221130170-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/d40d2fea8599/10.1177_14690667221130170-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/108f49a6dc66/10.1177_14690667221130170-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/66f72675632a/10.1177_14690667221130170-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/4d1413b1aade/10.1177_14690667221130170-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/b457083ba982/10.1177_14690667221130170-fig8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8739/9647320/6706b80b0005/10.1177_14690667221130170-fig9.jpg

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