Gmyrek D, Graupner K, Koch R, Schwarze R, Schulze A
Acta Paediatr Hung. 1987;28(1):1-8.
Ten underweight newborns with severe retinopathy of prematurity (ROP) and 18 newborns with slight changes in the sense of ROP were compared with 66 healthy infants. The distribution of 13 possibly pathogenetically effective features in these 3 groups of patients was studied by means of variance analysis. The greatest significance resulted for multiple blood transfusions and exchange transfusions. From this it was concluded that the toxic oxygen effect on the immature retina was probably more dependent on the venous PO2 (determined by Hb concentration, O2-affinity, arterial PO2, and blood flow) than on the isolated arterial PO2.
将10名患有严重早产儿视网膜病变（ROP）的低体重新生儿和18名ROP感觉有轻微变化的新生儿与66名健康婴儿进行了比较。通过方差分析研究了这三组患者中13种可能具有致病作用的特征的分布情况。多次输血和换血的意义最为显著。由此得出结论，有毒氧对未成熟视网膜的影响可能更多地取决于静脉血氧分压（由血红蛋白浓度、氧亲和力、动脉血氧分压和血流决定），而不是单独的动脉血氧分压。
