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Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection.

作者信息

Murphy M F, Metcalfe P, Waters A H, Carne C A, Weller I V, Linch D C, Smith A

出版信息

Br J Haematol. 1987 Jul;66(3):337-40. doi: 10.1111/j.1365-2141.1987.tb06920.x.

DOI:10.1111/j.1365-2141.1987.tb06920.x
PMID:3620353
Abstract

The incidence of lymphopenia, thrombocytopenia and neutropenia was studied in 105 homosexual men with HIV infection. Lymphopenia was common in patients with AIDS (75%), but its incidence in PGL (24%) was not significantly different from that in asymptomatic anti-HIV positive (15%) homosexual men. Neutropenia and thrombocytopenia were found in patients with AIDS or PGL, but not in asymptomatic anti-HIV positive homosexuals. The study suggests that the neutropenia and thrombocytopenia in these patients were due to autoimmune destruction of neutrophils and platelets.

摘要

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