运动学习后初级体感皮层的兴奋性和GABA能神经元活动的变化。
Changes in excitability and GABAergic neuronal activity of the primary somatosensory cortex after motor learning.
作者信息
Pham Manh Van, Saito Kei, Miyaguchi Shota, Watanabe Hiraku, Ikarashi Hitomi, Nagasaka Kazuaki, Yokota Hirotake, Kojima Sho, Inukai Yasuto, Otsuru Naofumi, Onishi Hideaki
机构信息
Department of Physical Therapy, Hai Duong Medical Technical University, Hai Duong, Vietnam.
Institute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Niigata, Japan.
出版信息
Front Neurosci. 2022 Sep 20;16:794173. doi: 10.3389/fnins.2022.794173. eCollection 2022.
INTRODUCTION
It is widely known that motor learning changes the excitability of the primary motor cortex. More recently, it has been shown that the primary somatosensory cortex (S1) also plays an important role in motor learning, but the details have not been fully examined. Therefore, we investigated how motor skill training affects somatosensory evoked potential (SEP) in 30 neurologically healthy subjects.
METHODS
SEP N20/P25_component and N20/P25 SEP paired-pulse depression (SEP-PPD) were assessed before and immediately after complex or simple visuomotor tasks.
RESULTS
Motor learning was induced more efficiently by the complex visuomotor task than by the simple visuomotor task. Both the N20/P25 SEP amplitude and N20/P25 SEP-PPD increased significantly immediately after the complex visuomotor task, but not after the simple visuomotor task. Furthermore, the altered N20/P25 SEP amplitude was associated with an increase in motor learning efficiency.
CONCLUSION
These results suggest that motor learning modulated primary somatosensory cortex excitability.
引言
众所周知，运动学习会改变初级运动皮层的兴奋性。最近有研究表明，初级体感皮层（S1）在运动学习中也起着重要作用，但具体细节尚未得到充分研究。因此，我们对30名神经系统健康的受试者进行了研究，以探讨运动技能训练如何影响体感诱发电位（SEP）。
方法
在复杂或简单的视觉运动任务前后，评估SEP的N20/P25成分和N20/P25 SEP配对脉冲抑制（SEP-PPD）。
结果
复杂视觉运动任务比简单视觉运动任务更有效地诱导运动学习。复杂视觉运动任务后，N20/P25 SEP波幅和N20/P25 SEP-PPD立即显著增加，而简单视觉运动任务后则无此现象。此外，N20/P25 SEP波幅的改变与运动学习效率的提高有关。
结论
这些结果表明运动学习可调节初级体感皮层的兴奋性。
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