Zahoor Hovra, Patel Ronak, El-Bahri Jessica
Internal Medicine, HCA Orange Park Hospital, Orange Park, USA.
Radiology, Baylor College of Medicine, Houston, USA.
Cureus. 2022 Sep 3;14(9):e28729. doi: 10.7759/cureus.28729. eCollection 2022 Sep.
Gout is a disease that occurs in response to the presence of monosodium urate (MSU) crystals typically within joints. Patients with gout may develop a chronic deposition of monosodium urate crystals within or around joints, cartilage, tendons, peri-articular, and subcutaneous tissue. This condition is termed "tophaceous gout." Ulceration of the skin by tophi is very uncommon. Literature regarding the clinical course and the management of ulcerated tophi is limited and, therefore, treatment options are not well established. We hereby present a case of a 46-year-old male who presented to our facility with poorly controlled polyarticular tophaceous gout complicated by ulcerated tophi. Our hope is to contribute to the limited knowledge of this rare disease process and to contribute toward formulating the best management approach.
痛风是一种通常因关节内存在尿酸单钠（MSU）晶体而引发的疾病。痛风患者的关节内、关节周围、软骨、肌腱、关节周围及皮下组织可能会出现尿酸单钠晶体的慢性沉积。这种情况被称为“痛风石性痛风”。痛风石导致皮肤溃疡非常罕见。关于溃疡性痛风石的临床病程及治疗的文献有限，因此，治疗方案尚未明确确立。我们在此报告一例46岁男性患者，他因多关节痛风石性痛风控制不佳并伴有溃疡性痛风石前来我院就诊。我们希望能为这种罕见疾病进程的有限知识做出贡献，并有助于制定最佳治疗方案。
