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青光眼手术后的虹膜后粘连:前房变浅和毛果芸香碱的加重作用。

Posterior synechiae after glaucoma operations: aggravation by shallow anterior chamber and pilocarpine.

作者信息

Phillips C I, Clark C V, Levy A M

出版信息

Br J Ophthalmol. 1987 Jun;71(6):428-32. doi: 10.1136/bjo.71.6.428.

DOI:10.1136/bjo.71.6.428
PMID:3620422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1041192/
Abstract

Posterior pupillary synechiae affect a proportion of eyes subjected to iridectomy with or without drainage operation because (1) aqueous humour bypasses the pupil; (2) traumatic iridocyclitis occurs; (3) there is immobility of the iris in the iridectomy sector; (4) in eyes with angle closure glaucoma closer apposition of the iris to the anterior lens capsule increases the tendency; (5) pilocarpine aggravates (4) both in angle closure glaucoma and open angle glaucoma and produces a small immobile pupil facilitating pupillary membrane formation (occlusio pupillae). Pilocarpine should be avoided if possible as medical treatment at any time after a drainage operation. A beta blocker is the drug of choice. To eliminate posterior synechiae over a fair number of degrees of pupil (say 30 degrees) sector iridectomy can be done.

摘要

瞳孔后粘连会影响一部分接受了虹膜切除术(无论是否进行引流手术)的眼睛,原因如下:(1)房水绕过瞳孔;(2)发生外伤性虹膜睫状体炎;(3)虹膜切除术区域的虹膜活动受限;(4)在闭角型青光眼患者中,虹膜与晶状体前囊更紧密的贴合增加了这种趋势;(5)毛果芸香碱在闭角型青光眼和开角型青光眼中都会加重(4)的情况,并产生一个小的固定瞳孔,促进瞳孔膜形成(瞳孔闭锁)。在引流手术后的任何时候,作为药物治疗,应尽可能避免使用毛果芸香碱。β受体阻滞剂是首选药物。为了消除相当程度(比如30度)的瞳孔后粘连,可以进行扇形虹膜切除术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0692/1041192/6d930b2f005b/brjopthal00616-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0692/1041192/6d930b2f005b/brjopthal00616-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0692/1041192/6d930b2f005b/brjopthal00616-0026-a.jpg

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本文引用的文献

1
Some observations on chronic closed-angle glaucoma.关于慢性闭角型青光眼的一些观察
Br J Ophthalmol. 1957 Apr;41(4):208-13. doi: 10.1136/bjo.41.4.208.
2
Closed-angle glaucoma; significance of sectoral variations in angle depth.闭角型青光眼;房角深度扇形变化的意义
Br J Ophthalmol. 1956 Mar;40(3):136-43. doi: 10.1136/bjo.40.3.136.
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Peripheral iridectomy in angle-closure glaucoma: a common complication.闭角型青光眼周边虹膜切除术:一种常见并发症。
毛果芸香碱对人角膜基质细胞的细胞毒性及其潜在的细胞毒性机制。
Int J Ophthalmol. 2016 Apr 18;9(4):505-11. doi: 10.18240/ijo.2016.04.05. eCollection 2016.
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Management of hypotony and flat anterior chamber associated with glaucoma filtration surgery.青光眼滤过手术相关的低眼压和无前房的处理
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Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study.小梁切除术后应用眼科粘弹剂注射治疗无前房:病例系列研究
Clin Ophthalmol. 2013;7:1781-5. doi: 10.2147/OPTH.S51165. Epub 2013 Sep 6.
6
Postoperative flat anterior chamber: incidence, risk factors, and effect on the long-term success of trabeculectomy.术后扁平前房:发生率、危险因素及对小梁切除术长期成功率的影响。
Jpn J Ophthalmol. 2013 Nov;57(6):520-8. doi: 10.1007/s10384-013-0274-4. Epub 2013 Aug 30.
Br J Ophthalmol. 1967 Nov;51(11):733-8. doi: 10.1136/bjo.51.11.733.
4
Surgical safety of prophylactic peripheral iridectomy.预防性周边虹膜切除术的手术安全性
Br J Ophthalmol. 1967 Jul;51(7):459-62. doi: 10.1136/bjo.51.7.459.
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Results of peripheral iridectomy in closed-angle glaucoma.闭角型青光眼周边虹膜切除术的结果
Br J Ophthalmol. 1969 Feb;53(2):110-5. doi: 10.1136/bjo.53.2.110.
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Am J Ophthalmol. 1968 Apr;65(4):548-52. doi: 10.1016/0002-9394(68)93872-5.
7
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