First Department of Obstetrics, Shijiazhuang Obstetrics and Gynecology Hospital, Shijiazhuang, Hebei, China.
Nursing Department, Shijiazhuang Fourth Hospital, Shijiazhuang, Hebei, China.
Dis Markers. 2022 Sep 27;2022:7584936. doi: 10.1155/2022/7584936. eCollection 2022.
To evaluate the effect of targeted care plus exercise intervention on blood glucose levels and maternal and newborn outcomes in patients with gestational diabetes mellitus (GDM).
A total of 96 patients with GDM admitted to our hospital between March 2018 and January 2020 were recruited and assigned to receive either routine nursing (routine group) or targeted care plus exercise intervention (study group) via random method, with 48 patients in each group. Outcome measures included blood glucose, immune function, maternal and newborn outcome, and nursing satisfaction.
The patients in the study group had significantly lower amniotic fluid index (AFI), weight at delivery, body mass index (BMI), and weight gain during pregnancy than patients in the routine group ( < 0.05). There was no statistically significant difference in blood glucose between the two groups of patients before the intervention ( > 0.05). Targeted care plus exercise intervention resulted in significantly lower levels of fasting blood glucose (FBG), 2 h postprandial blood glucose (2hPBG), and blood glucose before bed versus routine care ( < 0.05). The patients with targeted care plus exercise intervention had higher immunoglobulin G (IgG) and IgM levels; higher CD3+, CD4+, and CD8+ levels; and lower lgA levels versus those with routine care ( < 0.05). Targeted care plus exercise intervention was associated with a lower incidence of negative pregnancy outcomes and a higher satisfaction versus routine care ( < 0.05).
Targeted treatment plus exercise intervention efficiently controls blood glucose levels in GDM patients, improves immunological function, lowers the risk of pregnancy problems, improves pregnancy outcomes, and promotes patient satisfaction, indicating a high potential for therapeutic development. Targeted treatment combined with exercise intervention is encouraged following effective pharmacological interventions to facilitate recovery.
评估目标护理加运动干预对妊娠期糖尿病（GDM）患者血糖水平及母婴结局的影响。
选取我院 2018 年 3 月至 2020 年 1 月收治的 96 例 GDM 患者，采用随机数字表法分为常规护理（常规组）和目标护理加运动干预（研究组），各 48 例。观察两组患者血糖、免疫功能、母婴结局及护理满意度。
研究组患者羊水指数（AFI）、分娩时体重、体质量指数（BMI）、孕期体重增加值均低于常规组（ < 0.05）。两组患者干预前血糖比较差异无统计学意义（ > 0.05），目标护理加运动干预后空腹血糖（FBG）、餐后 2 小时血糖（2hPBG）、睡前血糖低于常规护理（ < 0.05）。目标护理加运动干预后患者免疫球蛋白 G（IgG）、IgM 水平升高，CD3+、CD4+、CD8+水平升高，免疫球蛋白 A（IgA）水平降低，与常规护理比较差异有统计学意义（ < 0.05）。目标护理加运动干预后不良母婴结局发生率低于常规护理，护理满意度高于常规护理（ < 0.05）。
目标治疗加运动干预可有效控制 GDM 患者血糖水平，改善免疫功能，降低妊娠不良结局风险，改善母婴结局，提高患者满意度，具有较高的治疗开发潜力。在有效的药物干预后，建议进行目标治疗联合运动干预，以促进康复。
