血液透析治疗并异时性双侧透明细胞肾细胞癌患者的联合免疫治疗：病例报告及文献综述
Combination immunotherapy in a patient with hemodialysis therapy and metachronous bilateral clear cell renal cell carcinoma: Case report and literature review.
作者信息
Isaza Alejandro Pineda, Franco Alvaro Osorio, Quintero González Lisceth Paola, Fajardo Marcela Vallejo
机构信息
Fellow of Hematology and Clinical Oncology, Health Sciences Faculty, Icesi University, Cali, Colombia.
Hematologist and Clinical Oncologist, Department of Hematoncology, Department of Internal Medicine, Fundación Valle del Lili, Cali, Colombia.
出版信息
Urol Case Rep. 2022 Sep 24;45:102242. doi: 10.1016/j.eucr.2022.102242. eCollection 2022 Nov.
Combination immunotherapy is a treatment strategy in patients with renal cell carcinoma that has proved to be effective in phase III randomized clinical trials. These studies do not include patients with end stage kidney disease on hemodialysis. We discuss this case about a patient with metachronous bilateral clear cell renal cell carcinoma, managed with bilateral nephrectomy and ulterior requirement of hemodialysis, with lung and intestinal progression, managed with combination immunotherapy, with a partial response and absence of adverse effects related to treatment.
联合免疫疗法是一种用于肾细胞癌患者的治疗策略，已在III期随机临床试验中证明有效。这些研究不包括接受血液透析的终末期肾病患者。我们讨论这个病例，患者为异时性双侧透明细胞肾细胞癌，接受双侧肾切除术及后续血液透析治疗，出现肺部和肠道进展，接受联合免疫疗法治疗，获得部分缓解且无治疗相关不良反应。
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