Asrarov M I, Gagel'gans A I, Tashmukhamedov B A
Biofizika. 1987 May-Jun;32(3):454-7.
It has been shown by using o-phthalic acid--a concurrent inhibitor of the transport of oxalacetic acid in mitochondria that the effect of the latter on the mechanism of 2H+/Ca2+-metabolism is realized at the inner side of the inner mitochondrial membrane. Oxalacetic acid was shown to induce not only the release of Ca2+ ions but also those of strontium and manganese accumulated in the mitochondria (100-150 nmol/mg of protein). Mechanism of the effect of oxalacetic acid on permeability of the mitochondria membranes are discussed.
通过使用邻苯二甲酸（草酰乙酸在线粒体中转运的同时抑制剂）已表明，草酰乙酸对2H⁺/Ca²⁺代谢机制的影响是在线粒体内膜的内侧实现的。已表明草酰乙酸不仅能诱导Ca²⁺离子释放，还能诱导线粒体中积累的锶和锰离子释放（100 - 150 nmol/mg蛋白质）。讨论了草酰乙酸对线粒体膜通透性影响的机制。
