基于金刚石的 MEAs 检测肾上腺嗜铬细胞量子胞吐的方法。
Methodologies for Detecting Quantal Exocytosis in Adrenal Chromaffin Cells Through Diamond-Based MEAs.
机构信息
Department of Drug Science and Technology and "NIS" Inter-departmental Centre, University of Torino, Turin, Italy.
Department of Drug Science and Technology, University of Torino, Turin, Italy.
出版信息
Methods Mol Biol. 2023;2565:213-221. doi: 10.1007/978-1-0716-2671-9_15.
Diamond-based multiarray sensors are suitable to detect in real-time exocytosis and action potentials from cultured, spontaneously firing chromaffin cells, primary hippocampal neurons, and midbrain dopaminergic neurons. Here, we focus on how amperometric measurements of catecholamine release are performed on micrographitic diamond multiarrays (μG-D-MEAs) with high temporal and spatial resolution by 16 electrodes simultaneously.
基于金刚石的多阵列传感器适用于实时检测培养的、自发放电的嗜铬细胞、原代海马神经元和中脑多巴胺能神经元中的胞吐作用和动作电位。在这里，我们重点介绍如何通过 16 个电极同时以高时间和空间分辨率在微图形金刚石多阵列（μG-D-MEAs）上进行儿茶酚胺释放的安培测量。
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