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[氧对白鼠视网膜光损伤的加重作用]

[Aggravating action of oxygen in light injury to the retina in the white rat].

作者信息

Kapusta N V, Zak P P, Fedorovich I B, Ostrovskiĭ M A, Skalatskiĭ O N

出版信息

Biull Eksp Biol Med. 1987 Jul;104(7):102-4.

PMID:3620635
Abstract

Rhodopsin concentration and "a"-wave ERG decrease, depending on illumination in the range of 360-380 nm have been investigated in albino rats. The dose of 1.8 J/cm2 proved sufficient for a decrease of "a"-wave ERG by 70% and for the reduction in rhodopsin concentration by 80%. The substitution of the air for O2 (1 or 2.5 ata) resulted in a considerable increase of photodamage of the retina.

摘要

已对白化病大鼠进行了研究,视紫红质浓度和“a”波视网膜电图(ERG)会根据360 - 380纳米范围内的光照而降低。1.8焦耳/平方厘米的剂量足以使“a”波ERG降低70%,视紫红质浓度降低80%。用氧气(1或2.5绝对大气压)替代空气会导致视网膜光损伤显著增加。

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