Tsibulevskiĭ A Iu, Ettinger A P
Biull Eksp Biol Med. 1987 Jul;104(7):38-40.
The influence of synthetic phenol antioxidants dibunol and BH-3 on the value of parietal pH has been studied in the stomach, duodenum, jejunum, ileum, caecum and rectum of intact and vagotomized rats 1, 7, 14, 30 and 60 days after treatment. It was shown that vagotomy leads to an increase in the stomach pH and to a decrease in pH in other parts of the gastrointestinal tract. Maximum BH-3 doses lead to pH increase in the stomach of intact rats. Chronic administration of therapeutic drug doses does not change pH value in control and vagotomized animals.
在完整和迷走神经切断的大鼠经治疗后1、7、14、30和60天，研究了合成酚类抗氧化剂二丁基羟基甲苯（dibunol）和BH - 3对胃、十二指肠、空肠、回肠、盲肠和直肠壁pH值的影响。结果表明，迷走神经切断术会导致胃pH值升高，而胃肠道其他部位的pH值降低。最大剂量的BH - 3会导致完整大鼠胃内pH值升高。长期给予治疗药物剂量对对照动物和迷走神经切断动物的pH值没有影响。
