在 COVID-19 长期感染期间和恢复期血浆治疗后缺乏 BTK 的髓系细胞表型
Phenotype of BTK-lacking myeloid cells during prolonged COVID-19 and upon convalescent plasma.
机构信息
Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
Serviço de Medicina II, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal.
出版信息
Eur J Haematol. 2023 Feb;110(2):209-212. doi: 10.1111/ejh.13881. Epub 2022 Oct 19.
Abstract
XLA patient with 7-month course of COVID-19 with persistent plasma SARS-CoV-2 load revealed a sustained non-inflammatory profile of myeloid cells in association with contained severity of disease, arguing in favor of the use of BTK inhibitors in SARS-COV-2 infection.
摘要
XLA 患者感染 COVID-19 病程长达 7 个月，持续性 SARS-CoV-2 血浆载量，揭示了与疾病严重程度可控相关的髓系细胞持续无炎症特征，支持在 SARS-CoV-2 感染中使用 BTK 抑制剂。
Zotero 插件