Department of Social Medicine, Sunprasitthiprasong Regional Hospital, Ubonratchathani, Thailand.
Strategy and Policy Division, National Health Security Office Region 10, Ubonratchathani, Thailand.
Sci Rep. 2022 Oct 8;12(1):16931. doi: 10.1038/s41598-022-20237-0.
There is little evidence to describe the burden of skin diseases in developing countries and its accuracy remained uncertain. We aimed to examine prevalence and disability adjusted life years (DALYs) of skin diseases in a Thai general population in Ubonratchathani. Based on real-world healthcare service data (diagnoses, prevalence, and cause-specific mortality) retrieved from the National Health Security Office reimbursement database, we used a simplified prevalence-based approach adopted in the Global Burden of Diseases to compute disease burden, measured as DALYs, of skin diseases. DALYs was calculated as the sum of years lost due to disability and years of life lost due to skin diseases, with adoption of previously published averaged disability weights and a 95% uncertainty interval (UI) estimated using a Bayesian bootstrap technique. From a total population of 1,503,945, 110,205 people were affected by skin disease in 2018-an overall prevalence of 7%. The prevalence varied across sex, age group and geographic areas. The most common skin diseases treated in Ubonratchathani's healthcare services were dermatitis, bacterial skin diseases and urticaria (prevalence of 2.35%, 2.21% and 0.89% respectively). Overall DALYs of skin diseases in Ubonratchathani population was 26,125 (95%UI 24,783-27,467), and this was relatively higher in men than women. (DALYs 13,717 (12,846-14,588) and 12,408 (11,417-13,399) for men and women respectively). The greatest contributors of DALYs were cellulitis, decubitus ulcer and contact dermatitis (11,680, 4,806 and 1,598 years respectively). In conclusion, skin disease caused substantial disease burden in this Thai population, with cellulitis being the largest contributor.
在发展中国家,有关皮肤病负担的证据很少,其准确性仍不确定。我们旨在研究乌汶叻差他尼的泰国一般人群中的皮肤病患病率和残疾调整生命年(DALY)。基于从国家健康保障办公室报销数据库中检索到的真实医疗保健服务数据(诊断、患病率和特定病因死亡率),我们使用了全球疾病负担中采用的简化基于患病率的方法来计算皮肤病的疾病负担,以 DALY 衡量。DALY 的计算方法是将因残疾而损失的年数和因皮肤病而损失的年数相加,采用先前发表的平均残疾权重和使用贝叶斯引导技术估计的 95%置信区间(UI)。在总人口 1503945 人中,2018 年有 110205 人患有皮肤病,患病率为 7%。患病率因性别、年龄组和地理位置而异。乌汶叻差他尼医疗服务中治疗最常见的皮肤病是皮炎、细菌性皮肤病和荨麻疹(患病率分别为 2.35%、2.21%和 0.89%)。乌汶叻差他尼人群中皮肤病的总 DALY 为 26125(95%UI 24783-27467),男性高于女性。(男性为 13717(12846-14588),女性为 12408(11417-13399)。DALY 最大的贡献者是蜂窝织炎、褥疮和接触性皮炎(分别为 11680、4806 和 1598 年)。总之,皮肤病在泰国人群中造成了相当大的疾病负担,蜂窝织炎是最大的贡献者。