National Hospital of Dermatology and Venereology, Hanoi 100000, Vietnam.
Department of Dermatology and Venereology, Hanoi Medical University, Hanoi 100000, Vietnam.
Int J Environ Res Public Health. 2019 Jan 23;16(3):305. doi: 10.3390/ijerph16030305.
Skin diseases have caused a heavy burden on the infected population worldwide. This study aimed to examine the health-related quality of life (HRQOL) among patients with different skin diseases and identify associated factors. A cross-sectional study with 430 participants was conducted at the Vietnam National Hospital of Dermatology and Venereology (NHD) from September to November 2018. The EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) instrument was employed, which measures the EQ-5D index from five domains including mobility, self-care, usual activity, pain/discomfort, and anxiety/depression. Multivariate Tobit regression was adopted to determine factors that were associated with HRQOL (EQ-5D index). The rate of atopic dermatitis was the highest with 28.8%, following by contact dermatitis (17.0%) and skin fungal infections (13.0%). Regarding HRQOL, anxiety/depression was the most common health problem in patients with skin diseases (71.8%), following by pain/discomfort (63.6%). The mean EQ-5D index score was 0.73 (SD = 0.19). The lowest EQ-5D index scores were obtained for females with skin infections (mean = 0.52) and for males with psoriasis (mean = 0.59). Females had significantly lower scores compared to males (Coef. = -0.06; 95% CI = -0.11 to -0.01). Higher income and living in rural areas were also negatively correlated with the EQ-5D index. This study demonstrated the low HRQOL among patients with skin diseases in Vietnam and emphasized the vulnerability of patients with different socioeconomic statuses to their HRQOL.
皮肤病在全球范围内给感染者带来了沉重的负担。本研究旨在探讨不同皮肤病患者的健康相关生活质量（HRQOL），并确定相关因素。2018 年 9 月至 11 月，在越南国家皮肤病与性病医院（NHD）进行了一项横断面研究，共纳入 430 名参与者。采用 EuroQol-5 维度-5 水平（EQ-5D-5L）量表评估，该量表从五个方面评估 EQ-5D 指数，包括行动能力、自我护理、日常活动、疼痛/不适和焦虑/抑郁。采用多元 Tobit 回归确定与 HRQOL（EQ-5D 指数）相关的因素。特应性皮炎的发病率最高，为 28.8%，其次是接触性皮炎（17.0%）和皮肤真菌感染（13.0%）。在 HRQOL 方面，焦虑/抑郁是皮肤病患者最常见的健康问题（71.8%），其次是疼痛/不适（63.6%）。EQ-5D 指数的平均得分为 0.73（SD=0.19）。皮肤感染的女性（平均=0.52）和银屑病的男性（平均=0.59）的 EQ-5D 指数得分最低。女性的得分明显低于男性（Coef.=-0.06；95%CI=-0.11 至-0.01）。较高的收入和居住在农村地区也与 EQ-5D 指数呈负相关。本研究表明越南皮肤病患者的 HRQOL 较低，并强调了不同社会经济地位的患者 HRQOL 的脆弱性。
