Altrup U
Brain Res. 1987 Jun 30;414(2):271-84. doi: 10.1016/0006-8993(87)90007-2.
The identified giant neurons B1 and B2 in the buccal ganglia of Helix pomatia were studied with electrophysiological and morphological techniques in order to establish a baseline for the study of neuronal communication in a relatively simple nervous system. Different synaptic inputs to neurons B1 and B2 were found to come from neurons of the buccal ganglia and to come via buccal nerves. In the epithelium of the pharynx, fibers of bipolar peripheral neurons could be stained, the central fibers of which probably contribute to the synaptic inputs of neurons B1 and B2. The dendrites of neurons B1 and B2 are mainly situated in anterior and lateral parts of the neuropil of the buccal ganglia, respectively. The axon of neuron B1 was traced to the esophagus/stomach. Intracellular stimulation of the neuron induces both a contraction of the longitudinally oriented fibers and an increase in the amplitude of spontaneously occurring peristaltic contractions of the esophagus. The axons of neuron B2 run to both salivary glands. Thin axon collaterals showing multiple swellings follow the bases of the epithelial cells of the salivary gland. The functioning of neurons B1 and B2, which are homologous to giant neurons in the buccal ganglia of other molluscs, is discussed.
为了在一个相对简单的神经系统中为神经元通讯研究建立一个基线，运用电生理和形态学技术对鉴定出的苹果螺颊神经节中的巨型神经元B1和B2进行了研究。发现对神经元B1和B2的不同突触输入来自颊神经节的神经元，并通过颊神经传入。在咽上皮中，双极外周神经元的纤维可以被染色，其中央纤维可能对神经元B1和B2的突触输入有贡献。神经元B1和B2的树突分别主要位于颊神经节神经纤维网的前部和外侧部分。神经元B1的轴突延伸至食管/胃。对该神经元进行细胞内刺激会诱导纵向排列的纤维收缩，并使食管自发蠕动收缩的幅度增加。神经元B2的轴突通向两个唾液腺。显示多个膨体的细轴突侧支沿着唾液腺上皮细胞的基部延伸。讨论了与其他软体动物颊神经节中的巨型神经元同源的神经元B1和B2的功能。
