Cognitive Neuroscience Department, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Maastricht Brain Imaging Center (M-BIC), Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, the Netherlands.
Cogn Neurosci. 2022 Jul;13(3-4):212-214. doi: 10.1080/17588928.2022.2131746. Epub 2022 Oct 9.
Recent studies suggest the hippocampus is involved in working memory (WM). Slotnick (this issue) critically reviewed relevant fMRI findings and concludes WM 'does not activate the hippocampus.' We extend Slotnick's review by discussing observations from human intracranial and lesion research. These studies do suggest hippocampal contributions to WM (beyond novelty encoding), which however are difficult to capture with conventional fMRI. Still, the advent of new fMRI techniques combined with a stronger emphasis on shared hippocampal mechanisms across short- and long-term memory pave an exciting path forward.
最近的研究表明，海马体参与了工作记忆（WM）。Slotnick（本期）对相关 fMRI 研究结果进行了批判性回顾，并得出 WM“不会激活海马体”的结论。我们通过讨论人类颅内和损伤研究的观察结果扩展了 Slotnick 的综述。这些研究确实表明海马体对 WM 有贡献（不仅仅是对新奇性的编码），但这很难用传统的 fMRI 技术捕捉到。尽管如此，新的 fMRI 技术的出现，以及对短期和长期记忆中海马体机制的更强烈关注，为未来的研究开辟了一条令人兴奋的道路。
