Department of Psychology, University of Notre Dame, Notre Dame, IN, USA.
Cogn Neurosci. 2022 Jul;13(3-4):215-217. doi: 10.1080/17588928.2022.2131749. Epub 2022 Oct 11.
Working memory (WM) and long-term memory (LTM) tests have both overlapping and distinct neurocognitive processes. Hippocampal activity in fMRI studies-a hallmark of LTM-also occurs on WM tasks, typically during encoding or retrieval and sometimes (albeit rarely) through 'late-delay' periods. The Synaptic Theory of WM suggests that 'activity-silent' synaptic weights retain temporary, WM-relevant codes without sustained, elevated activity. The hippocampus temporarily retains item-context bindings during WM-delays that are typically 'silent' to fMRI, probably via oscillatory patterns of informational connectivity among task-relevant regions of cortex. Advancing WM theory will require modeling this dynamic interplay, as in the 'Dynamic Processing Model of WM.
工作记忆 (WM) 和长时记忆 (LTM) 测试都具有重叠和独特的神经认知过程。功能磁共振成像 (fMRI) 研究中的海马体活动——LTM 的标志——也出现在 WM 任务中，通常在编码或检索期间，有时（尽管很少）在“延迟”期间出现。WM 的突触理论表明，“活动沉默”的突触权重保留了与 WM 相关的临时代码，而没有持续的、升高的活动。海马体在 WM 延迟期间暂时保留项目-上下文绑定，通常对 fMRI 是“沉默”的，可能是通过皮质中与任务相关的区域之间信息连通性的振荡模式。推进 WM 理论需要对这种动态相互作用进行建模，就像在“WM 的动态处理模型”中一样。
