Geer B W, Kamiak S N, Kidd K R, Nishimura R A, Yemm S J
J Exp Zool. 1976 Jan;195(1):15-32. doi: 10.1002/jez.1401950103.
Wild-type third instar larvae of Drosophilia melanogaster fed a casein-sucrose synthetic diet supplemented with phosphatidylcholine (4 mg/ml) possessed 33% more tissue lipid and a modified fatty acid profile compared to larvae fed a fat free-sucrose diet. The rates of lipid synthesis and pentose shunt activity were 2.1 and 2.2 times greater respectively in larvae fed the fat free-sucrose diet than in fat-sucrose fed animals. The tissue concentrations of acetyl-CoA and acyl-CoA were 80 and 61% higher respectively, CoA 49% lower, and the NADPH/NADP+ ratio greater in fat-sucrose fed larvae than in larvae fed a fat free-sucrose diet. Thus, larvae effectively utilized dietary lipid for lipid synthesis and as a supplementary energy source to carbohydrate.
与喂食无脂蔗糖饮食的果蝇幼虫相比，喂食添加了磷脂酰胆碱（4毫克/毫升）的酪蛋白 - 蔗糖合成饮食的野生型黑腹果蝇三龄幼虫的组织脂质多33%，且脂肪酸谱有所改变。喂食无脂蔗糖饮食的幼虫的脂质合成速率和戊糖磷酸途径活性分别比喂食脂肪 - 蔗糖饮食的动物高2.1倍和2.2倍。喂食脂肪 - 蔗糖饮食的幼虫的组织中乙酰辅酶A和酰基辅酶A的浓度分别比喂食无脂蔗糖饮食的幼虫高80%和61%，辅酶A低49%，且NADPH/NADP + 比值更高。因此，幼虫有效地利用膳食脂质进行脂质合成，并作为碳水化合物的补充能量来源。
