Rupnik Zsófia, Elekes Ágnes, Vámosi Péter
Péterfy Sándor Street Hospital‑Clinic, Jenő Manninger National Trauma Institute, Budapest, Hungary.
Saudi J Ophthalmol. 2022 Aug 29;36(2):183-188. doi: 10.4103/sjopt.sjopt_191_21. eCollection 2022 Apr-Jun.
Report experience regarding an anterior capsulotomy fixated intraocular lens (IOL) designed to prevent negative dysphotopsia (ND).
A prospective, nonrandomized clinical study was done at Péterfy Sándor Street Hospital-Clinic, and Jenő Manninger National Trauma Institute, Budapest, Hungary. The Morcher (Masket) 90S IOL has a circumferential groove on the optic that captures the anterior capsulotomy. Thus, part of the optic projects over and anterior to the capsule edge, while the bulk of the IOL is fixated within the capsular bag. We implanted the first version of the 90S IOL into the 40 eyes of 38 patients. These 40 eyes made up the primary investigational cohort. An additional 22 eyes received a modified version of the 90S IOL. The main outcome measure was the presence of ND. There was also a control group of 40 patients who received a single-piece monofocal aspheric hydrophobic acrylic IOL (877 FAB, Medicontur, Budapest, Hungary).
None of our 66 test patients experienced ND during the follow-up period. After specific questioning, six patients reported nondebilitating PD that improved or disappeared completely in 5 cases. For the 40 eyes of the control group, there were 10 cases of ND on the first postoperative day and in 2 cases ND persisted for more than 1 year postoperatively.
The 90S IOL can be used successfully to prevent ND. Since it is fixated by the anterior capsulotomy, additional advantages such as prevention of anterior capsule contraction, limited tilt, stable toric axis, perfect centration on the visual axis, and a more predictable lens position, among others, may be expected, and are under investigation.
报告关于一种旨在预防负性 dysphotopsia（ND）的前囊切开固定人工晶状体（IOL）的经验。
在匈牙利布达佩斯的彼得菲·山多尔街医院诊所和耶诺·曼宁格国家创伤研究所进行了一项前瞻性、非随机临床研究。莫彻（马斯基特）90S IOL 在光学部有一个圆周凹槽，可捕获前囊切开处。因此，光学部的一部分突出于囊膜边缘上方和前方，而 IOL 的大部分固定在囊袋内。我们将第一代 90S IOL 植入 38 例患者的 40 只眼中。这 40 只眼构成了主要研究队列。另外 22 只眼接受了改良版的 90S IOL。主要观察指标是 ND 的存在情况。还有一个由 40 例患者组成的对照组，他们接受了单片单焦点非球面疏水丙烯酸 IOL（877 FAB，匈牙利布达佩斯的 Medicontur）。
我们的 66 例受试患者在随访期间均未出现 ND。经过特定询问，6 例患者报告了不严重的 PD，其中 5 例有所改善或完全消失。对于对照组的 40 只眼，术后第一天有 10 例出现 ND，2 例术后 ND 持续超过 1 年。
90S IOL 可成功用于预防 ND。由于它通过前囊切开固定，可能会有其他优点，如预防前囊收缩、减少倾斜、稳定散光轴、在视轴上完美居中以及晶状体位置更可预测等，目前正在研究中。
