皮肤默克尔细胞癌（MCC）伴胃转移诊断后，因症状性贫血行部分胃切除术。
Partial Gastric Resection for Symptomatic Anemia following Diagnosis of Merkel Cell Carcinoma (MCC) of the Skin with Gastric Metastasis.
作者信息
Eagle Zachary, Essien Francis, Shahin George, Jones Amia, McKee John, Elkins Camille, Juakiem Wassem
机构信息
Department of Internal Medicine, Keesler Medical Center, Keesler Air Force Base, Biloxi, MS, USA.
Department of Internal Medicine, David Grant Medical Center, Travis Air Force Base, Fairfield, CA, USA.
出版信息
Clin Med Insights Case Rep. 2022 Oct 3;15:11795476221112382. doi: 10.1177/11795476221112382. eCollection 2022.
UNLABELLED
Merkel Cell Carcinoma (MCC) is a rare dermatologic malignancy with significant morbidity and mortality associated with metastatic disease. In this case, we discuss and extremely rare presentation of MCC with metastasis to the stomach in a patient that presented with profound anemia. Unfortunately, mortality following diagnosis of MCC with gastric metastasis approaches 67% at 4 months based on available published reports. Due to its rarity and high rate of mortality, there is a lack of available research and literature to help guide treatment of this rare presentation of MCC. This case report presents a positive outcome associated with a partial gastrectomy for the treatment of symptomatic MCC with gastric metastasis and continued survival with persistently stable hemoglobin at 12 months.
KEY CLINICAL MESSAGE
Anemia may be a significant cause of the morbidity and mortality associated with MCC with gastric metastasis. Our case demonstrates a positive outcome associated with partial gastric resection and presents a possible treatment option for this rare disease process.
未标注
默克尔细胞癌（MCC）是一种罕见的皮肤恶性肿瘤，与转移性疾病相关的发病率和死亡率都很高。在本病例中，我们讨论了一名患有严重贫血的患者出现极为罕见的MCC转移至胃部的情况。不幸的是，根据现有已发表报告，诊断为伴有胃转移的MCC后，4个月时的死亡率接近67%。由于其罕见性和高死亡率，缺乏可用的研究和文献来指导这种罕见的MCC表现的治疗。本病例报告展示了因对有症状的伴有胃转移的MCC进行部分胃切除而产生的积极结果，且患者在12个月时血红蛋白持续稳定，持续存活。
关键临床信息
贫血可能是与伴有胃转移的MCC相关的发病率和死亡率的重要原因。我们的病例展示了与部分胃切除相关的积极结果，并为这种罕见的疾病过程提供了一种可能的治疗选择。
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