Osama Md Ali, Rao Seema, Mittal Tarun, Kumar Sandeep
Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
Department of Histopathology, Sir Gangaram Hospital, New Delhi, India.
J Lab Physicians. 2023 Jan 18;15(3):466-469. doi: 10.1055/s-0042-1760670. eCollection 2023 Sep.
Merkel cell carcinoma (MCC) is a rare primary neuroendocrine tumor of the skin. It has an aggressive biological behavior and shows early local and distant metastasis. Diagnosis of MCC is a challenge and requires confirmation by immunohistochemistry (IHC). However, metastasis of MCC to the stomach is extremely uncommon and is rarely reported in the literature. We hereby describe a patient with gastric metastasis of MCC, who presented with black tarry stool and was finally diagnosed on the basis of clinical history, histology, and IHC.
默克尔细胞癌(MCC)是一种罕见的原发性皮肤神经内分泌肿瘤。它具有侵袭性生物学行为,早期即可出现局部和远处转移。MCC的诊断具有挑战性,需要通过免疫组织化学(IHC)进行确诊。然而,MCC转移至胃极为罕见,文献中鲜有报道。我们在此描述一例发生胃转移的MCC患者,该患者表现为黑便,最终根据临床病史、组织学检查和免疫组织化学检查得以确诊。