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皮肤原发性神经内分泌肿瘤的胃转移:罕见肿瘤的罕见表现。

Gastric Metastasis of Primary Neuroendocrine Tumor of Skin: Rare Tumor with Rare Presentation.

作者信息

Osama Md Ali, Rao Seema, Mittal Tarun, Kumar Sandeep

机构信息

Department of Pathology, Lady Hardinge Medical College, New Delhi, India.

Department of Histopathology, Sir Gangaram Hospital, New Delhi, India.

出版信息

J Lab Physicians. 2023 Jan 18;15(3):466-469. doi: 10.1055/s-0042-1760670. eCollection 2023 Sep.

Abstract

Merkel cell carcinoma (MCC) is a rare primary neuroendocrine tumor of the skin. It has an aggressive biological behavior and shows early local and distant metastasis. Diagnosis of MCC is a challenge and requires confirmation by immunohistochemistry (IHC). However, metastasis of MCC to the stomach is extremely uncommon and is rarely reported in the literature. We hereby describe a patient with gastric metastasis of MCC, who presented with black tarry stool and was finally diagnosed on the basis of clinical history, histology, and IHC.

摘要

默克尔细胞癌(MCC)是一种罕见的原发性皮肤神经内分泌肿瘤。它具有侵袭性生物学行为,早期即可出现局部和远处转移。MCC的诊断具有挑战性,需要通过免疫组织化学(IHC)进行确诊。然而,MCC转移至胃极为罕见,文献中鲜有报道。我们在此描述一例发生胃转移的MCC患者,该患者表现为黑便,最终根据临床病史、组织学检查和免疫组织化学检查得以确诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0a2/10411111/ff7637532eba/10-1055-s-0042-1760670-i2271337-1.jpg

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