石墨相氮化碳复合分子印迹微球结合超高效液相色谱法测定乳制品中的有机磷
Determination of organophosphorus in dairy products by graphitic carbon nitride combined molecularly imprinted microspheres with ultra performance liquid chromatography.
作者信息
Pan Yinchuan, Liu Xu, Liu Jing, Wang Jianping, Liu Juxiang, Gao Yanxia, Ma Ning
机构信息
College of Veterinary Medicine, Veterinary Biological Technology Innovation Center of Hebei Province, Hebei Agricultural University, Baoding, Hebei 071001, PR China.
College of Animal Science, Hebei Agricultural University, Baoding, Hebei 071001, PR China.
出版信息
Food Chem X. 2022 Aug 9;15:100424. doi: 10.1016/j.fochx.2022.100424. eCollection 2022 Oct 30.
Organophosphorus (OPPs) residues in dairy products are a potential threat to human health. To extract trace amounts of OPPs in dairy products, a graphitic carbon nitride (g-CN) was synthesized and combined with OPPs-based molecularly imprinted microspheres (MIM) to create a composite material (MIM/g-CN). Then, the MIM/g-CN was used to prepare a solid phase extraction (SPE) cartridge to detect the OPPs in dairy products with UPLC method. The specific surface area of MIM/g-CN was 172.208 m/g, good thermal stability under 300℃, and could reuse up to 15 times. The four OPPs had good linear relationship within the range of 1-10000 ng/mL ( > 0.999). The limits of detection were 0.7-2.6 ng/mL, and recoveries from blank dairy samples were 86.4 to 95.3 %. In this study, MIM combined with g-CN was firstly utilized for the detection of OPPs in dairy products, which indicated it might be an ideal adsorbent for dairy products pretreatment.
乳制品中的有机磷残留物对人类健康构成潜在威胁。为了提取乳制品中的痕量有机磷，合成了一种石墨相氮化碳（g-CN），并将其与基于有机磷的分子印迹微球（MIM）结合，制备了一种复合材料（MIM/g-CN）。然后，使用MIM/g-CN制备固相萃取（SPE）柱，采用超高效液相色谱法检测乳制品中的有机磷。MIM/g-CN的比表面积为172.208 m/g，在300℃以下具有良好的热稳定性，可重复使用15次。四种有机磷在1-10000 ng/mL范围内具有良好的线性关系（r>0.999）。检测限为0.7-2.6 ng/mL，空白乳制品样品的回收率为86.4%至95.3%。本研究首次将MIM与g-CN结合用于乳制品中有机磷的检测，表明其可能是乳制品预处理的理想吸附剂。
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