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性别与院外心脏骤停的发病率、临床特征及预后的关联:中东地区视角

Gender Association with Incidence, Clinical Profile, and Outcome of Out-of-Hospital Cardiac Arrest: A Middle East Perspective.

作者信息

Khazaal Fadi, Arabi Abdulrahman, Patel Ashfaq, Singh Rajvir, Al Suwaidi Jassim Mohd, Al-Qahtani Awad, Arafa Salaheddin Omran, Asaad Nidal, Hajar Hajar A

机构信息

Department of Adult Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.

出版信息

Heart Views. 2022 Apr-Jun;23(2):67-72. doi: 10.4103/heartviews.heartviews_73_21. Epub 2022 Jul 23.

Abstract

BACKGROUND

Out-of-hospital cardiac arrest (OHCA) is a leading cause of death worldwide. However, there is limited information on the outcome of the OHCA in the Middle East population, and limited studies have been carried out in the Arab Gulf countries. Hence, we aim to study the incidence and rate of survival in the OHCA setting and to assess the impact of gender on the clinical outcome following OHCA.

METHODS

Retrospective analysis of a prospective registry of all eligible, consecutive, and nontraumatic adult patients who successfully resuscitated (return of spontaneous circulation) from "Cardiac Arrest" occurring outside the hospital, Hospitalized in Doha, Qatar from January 1991 to June 2010.

RESULTS

A total of 41,453 consecutive patients were admitted during the study, of whom 987 (2.4%) had a diagnosis of OHCA. Among them, 269 (27.3%) were women and 718 (72.7%) were men. Although the mortality rate was higher in females than in males (65.4% vs. 57.7%, = 0.03), the logistic regression analysis did not show gender as an independent predictor of death in this clinical setting.

CONCLUSION

In this sample of the state population, women who have OHCAs had a lower rate of survival, but gender was not an independent predictor of mortality following OHCA.

摘要

背景

院外心脏骤停(OHCA)是全球主要的死亡原因之一。然而,关于中东人群院外心脏骤停结局的信息有限,且在阿拉伯海湾国家开展的相关研究较少。因此,我们旨在研究院外心脏骤停情况下的发病率和生存率,并评估性别对院外心脏骤停后临床结局的影响。

方法

对1991年1月至2010年6月在卡塔尔多哈住院的所有符合条件、连续且非创伤性的成年患者进行前瞻性登记,这些患者因院外发生的“心脏骤停”成功复苏(自主循环恢复)。

结果

研究期间共收治41453例连续患者,其中987例(2.4%)诊断为院外心脏骤停。其中,女性269例(27.3%),男性718例(72.7%)。尽管女性死亡率高于男性(65.4%对57.7%,P = 0.03),但逻辑回归分析未显示在该临床环境中性别是死亡的独立预测因素。

结论

在该国家人群样本中,发生院外心脏骤停的女性生存率较低,但性别并非院外心脏骤停后死亡率的独立预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02e5/9542974/2bd594b38c78/HV-23-67-g001.jpg

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