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医学生睡眠质量不佳风险预测数学列线图的开发与验证

Development and validation of mathematical nomogram for predicting the risk of poor sleep quality among medical students.

作者信息

Ding Jiahao, Guo Xin, Zhang Mengqi, Hao Mingxia, Zhang Shuang, Tian Rongshen, Long Liting, Chen Xiao, Dong Jihui, Song Haiying, Yuan Jie

机构信息

School of Psychology and Mental Health, North China University of Science and Technology, Tangshan, China.

Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, China.

出版信息

Front Neurosci. 2022 Sep 23;16:930617. doi: 10.3389/fnins.2022.930617. eCollection 2022.

Abstract

BACKGROUND

Despite the increasing prevalence of poor sleep quality among medical students, only few studies have identified the factors associated with it sing methods from epidemiological surveys. Predicting poor sleep quality is critical for ensuring medical Students' good physical and mental health. The aim of this study was to develop a comprehensive visual predictive nomogram for predicting the risk of poor sleep quality in medical students.

METHODS

We investigated medical Students' association with poor sleep quality at JiTang College of North China University of Science and Technology through a cross-sectional study. A total of 5,140 medical students were randomized into a training cohort (75%) and a validation cohort (25%). Univariate and multivariate logistic regression models were used to explore the factors associated with poor sleep quality. A nomogram was constructed to predict the individual risk of poor sleep quality among the medical students studied.

RESULTS

31.9% of medical students in the study reported poor sleep quality. We performed multivariate logistic analysis and obtained the final model, which confirmed the risk and protective factors of poor sleep quality ( < 0.05). Protective factors included the absence of physical discomfort (OR = 0.638, 95% CI: 0.546-0.745). Risk factors included current drinking (OR = 0.638, 95% CI: 0.546∼0.745), heavy study stress (OR = 2.753, 95% CI: 1.456∼5.631), very heavy study stress (OR = 3.182, 95% CI: 1.606∼6.760), depressive symptoms (OR = 4.305, 95% CI: 3.581∼5.180), and anxiety symptoms (OR = 1.808, 95% CI: 1.497∼2.183). The area under the ROC curve for the training set is 0.776 and the area under the ROC curve for the validation set is 0.770, which indicates that our model has good stability and prediction accuracy. Decision curve analysis and calibration curves demonstrate the clinical usefulness of the predictive nomograms.

CONCLUSION

Our nomogram helps predict the risk of poor sleep quality among medical students. The nomogram used includes the five factors of drinking, study stress, recent physical discomfort, depressive symptoms, and anxiety symptoms. The model has good performance and can be used for further research on and the management of the sleep quality of medical students.

摘要

背景

尽管医学生睡眠质量差的患病率不断上升,但只有少数研究采用流行病学调查方法确定与之相关的因素。预测睡眠质量差对于确保医学生良好的身心健康至关重要。本研究的目的是开发一种综合视觉预测列线图,用于预测医学生睡眠质量差的风险。

方法

我们通过横断面研究调查了华北理工大学冀唐学院医学生与睡眠质量差的相关性。总共5140名医学生被随机分为训练队列(75%)和验证队列(25%)。单因素和多因素逻辑回归模型用于探索与睡眠质量差相关的因素。构建了一个列线图来预测所研究医学生个体睡眠质量差的风险。

结果

研究中有31.9%的医学生报告睡眠质量差。我们进行了多因素逻辑分析并获得了最终模型,该模型确定了睡眠质量差的风险因素和保护因素(P<0.05)。保护因素包括无身体不适(OR=0.638,95%CI:0.546-0.745)。风险因素包括当前饮酒(OR=0.638,95%CI:0.546∼0.745)、学习压力大(OR=2.753,95%CI:1.456∼5.631)、学习压力非常大(OR=3.182,95%CI:1.606∼6.760)、抑郁症状(OR=4.305,95%CI:3.581∼5.180)和焦虑症状(OR=1.808,95%CI:1.497∼2.183)。训练集的ROC曲线下面积为0.776,验证集的ROC曲线下面积为0.770,这表明我们的模型具有良好的稳定性和预测准确性。决策曲线分析和校准曲线证明了预测列线图的临床实用性。

结论

我们的列线图有助于预测医学生睡眠质量差的风险。所使用的列线图包括饮酒、学习压力、近期身体不适、抑郁症状和焦虑症状这五个因素。该模型性能良好,可用于进一步研究和管理医学生的睡眠质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d181/9537862/e04019f2d98b/fnins-16-930617-g001.jpg

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