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[儿童睾丸良性囊性肿瘤]

[Benign cystic tumors of the testis in children].

作者信息

Van Kote G, Leconte D, Renault D, Godefroy Y, Charbonnel E

出版信息

Chir Pediatr. 1987;28(2):102-7.

PMID:3621386
Abstract

Benign cystic testicular tumors are very uncommon in childhood. These tumors can be dysplasic or teratomatous forming two peculiar groups. First electively affect the rete testis cells realizing simple cysts or multicystic dysplasia. The authors report one case of simple cyst in a four months old boy and analyse the eight observations of the literature of similar localisation and histologic structure. Dysplasic cysts are always surrounded by cuboidal or flatted epithelium and their contain is a clear liquid. The cystic dilatation of the rete testis would be consecutive to a defect of junction between the two different embryologic formations of the testicle and its excretor system. The primitive perturbation would affect the mesonephrotic formations sometimes partial cause of simple cysts, elsewhere more extensive responsible of the multicystic dysplasia associated in maximum cases with urinary system malformations. Liquid of the cysts would be the consequence of a very early accentuation of the rete cells secretion. In a second part, the different sorts of benign cystic teratomas are exposed, in order: epidermoid cysts, dermoid cysts and benign mature teratomas. For each of them are related their histologic structure and the frequency in consideration of literature analysis. These teratomatous cystic tumors would be results of a same tumoral process of increasing differentiation. They are benign under condition to be perfectly pure, examination of the whole piece is mandatory. All these benign tumors are commonly revealed by a large isolated testicle, the echography and negative biological evaluation (alpha foetoprotein, gonadotrophin hormones) may lead to suspect the type of tumor but histology only makes the diagnosis.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

良性囊性睾丸肿瘤在儿童时期非常罕见。这些肿瘤可以是发育异常性或畸胎瘤性的,形成两个特殊的类别。第一类选择性地影响睾丸网细胞,形成单纯囊肿或多囊性发育异常。作者报告了一例4个月大男孩的单纯囊肿病例,并分析了文献中8例类似部位和组织结构的观察结果。发育异常性囊肿总是被立方上皮或扁平上皮所包围,其内容物为清亮液体。睾丸网的囊性扩张可能是由于睾丸及其排泄系统两种不同胚胎形成之间连接缺陷所致。最初的扰动会影响中肾结构,有时是单纯囊肿的部分原因,在其他情况下更广泛,是大多数伴有泌尿系统畸形的多囊性发育异常的原因。囊肿液是睾丸网细胞分泌过早增强的结果。在第二部分中,依次介绍了不同类型的良性囊性畸胎瘤:表皮样囊肿、皮样囊肿和良性成熟畸胎瘤。根据文献分析,分别阐述了它们的组织结构和发生率。这些畸胎瘤性囊性肿瘤是同一肿瘤分化过程的结果。它们在完全纯净的情况下是良性的,必须对整个标本进行检查。所有这些良性肿瘤通常表现为单个大睾丸,超声检查和阴性生物学评估(甲胎蛋白、促性腺激素)可能提示肿瘤类型,但只有组织学检查才能确诊。(摘要截断于250字)

相似文献

1
[Benign cystic tumors of the testis in children].[儿童睾丸良性囊性肿瘤]
Chir Pediatr. 1987;28(2):102-7.
2
[Simple cysts of the testis in children. Apropos of 2 cases].
J Urol (Paris). 1988;94(4):227-31.
3
Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues.性腺生殖细胞肿瘤:一篇选择性综述,重点强调鉴别诊断中的问题、新认识的问题及有争议的问题。
Mod Pathol. 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310.
4
[Nongerminal, benign testicular tumors--report of experiences].[非生殖性良性睾丸肿瘤——经验报告]
Urologe A. 1988 Mar;27(2):96-8.
5
Ovarian and paraovarian squamous-lined cysts (epidermoid cysts): a clinicopathologic study of 18 cases with comparison to mature cystic teratomas.卵巢及卵巢旁衬覆鳞状上皮的囊肿(表皮样囊肿):18例临床病理研究并与成熟囊性畸胎瘤对比
Int J Gynecol Pathol. 2009 Mar;28(2):193-6. doi: 10.1097/PGP.0b013e318187e147.
6
[Unusual tumors of the testis. Apropos of 22 cases].[睾丸罕见肿瘤。附22例报告]
Ann Urol (Paris). 1991;25(4):194-8.
7
Interphase fluorescence in situ hybridization analysis of chromosome 12p abnormalities is useful for distinguishing epidermoid cysts of the testis from pure mature teratoma.12号染色体短臂异常的间期荧光原位杂交分析有助于鉴别睾丸表皮样囊肿与单纯成熟畸胎瘤。
Clin Cancer Res. 2006 Oct 1;12(19):5668-72. doi: 10.1158/1078-0432.CCR-06-0976.
8
Sacrococcygeal developmental abnormalities and tumors in children.儿童骶尾部发育异常与肿瘤
Perspect Pediatr Pathol. 1984 Spring;8(1):9-56.
9
[Epidermoid cyst, a benign tumor of the testes. Concerning 2 cases (author's transl)].表皮样囊肿,睾丸的一种良性肿瘤。关于2例(作者译)
J Urol Nephrol (Paris). 1975 Oct-Nov;81(10-11):769-73.
10
[Malignant transformation of thyroid tissue in an ovarian dermoid cyst: case report].[卵巢皮样囊肿中甲状腺组织的恶性转化:病例报告]
Med Pregl. 1999 Sep-Oct;52(9-10):395-8.