CNNC Nuclear Power Operations Management Co., Ltd, Haiyan, 314300, China.
College of Material and Textile Engineering, Nanotechnology Research Institute, Jiaxing University, Jiaxing, 314001, China.
Soft Matter. 2022 Oct 26;18(41):7959-7967. doi: 10.1039/d2sm00936f.
The exploration of biodegradable polymers with shape memory effects (SMEs) holds great promise in biomedical fields. Revealing the relationship between the SMEs and polymer structures not only contributes to interpreting the SME mechanisms, but also prompts the customization of materials properties for specific requirements. Herein, we developed a series of poly(ester urea) (PEU) random copolymers composed of two different diamine monomers based on L-alanine and L-valine, respectively. It was shown that the shape memory performance of the PEU copolymers strongly depended on the composition of two different diamine monomers in the PEU copolymers and other physical properties. This tunability likely arose from the change of polymer chain mobility and crystallinity, which were impacted by the choice of α-amino acids. Intriguingly, thin films of the PEU copolymers exhibited a high strain at break of 347-743% around the physiological temperature (35 °C). Moreover, the random copolymerization of two different sorts of diamine monomers has been demonstrated as a facile approach to precisely tailor the physical properties of the PEUs according to custom needs.
具有形状记忆效应（SMEs）的可生物降解聚合物的探索在生物医学领域具有巨大的应用前景。揭示 SME 与聚合物结构之间的关系不仅有助于解释 SME 机制，还有助于根据特定要求定制材料性能。在这里，我们开发了一系列基于 L-丙氨酸和 L-缬氨酸的两种不同二胺单体的聚（酯脲）（PEU）无规共聚物。结果表明，PEU 共聚物的形状记忆性能强烈依赖于 PEU 共聚物中两种不同二胺单体的组成和其他物理性能。这种可调节性可能源于聚合物链迁移率和结晶度的变化，而这又受到α-氨基酸选择的影响。有趣的是，PEU 共聚物的薄膜在生理温度（35°C）附近表现出高达 347-743%的高断裂伸长率。此外，两种不同类型二胺单体的无规共聚已被证明是一种根据定制需求精确调整 PEU 物理性能的简便方法。
