HU University of Applied Science, Research group Innovation in Preventive Healthcare, Utrecht, The Netherlands.
Oral Public Health Department, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
PLoS One. 2022 Oct 10;17(10):e0275501. doi: 10.1371/journal.pone.0275501. eCollection 2022.
This scoping review aims to identify complex health interventions (CHI's) to prevent early childhood caries (ECC), explore the level of complexity of the identified CHI's, and explore the details of their development, evaluation, and implementation.
Many interventions to prevent ECC have multiple interacting components and can be seen as CHI's. Recent reviews on these interventions have found inconclusive effects, which may be due to differences in the development, evaluation, and implementation of CHI's.
This scoping review will consider clinical trials reporting CHI's to prevent ECC that starts during pregnancy or in the first year of life. Studies in the English language will be included regardless of the country of origin, sociocultural setting, or context.
This review will follow the Joanna Briggs Institute methodology for scoping reviews. An initial search of PubMed identified keywords and Medical Subject Headings terms. A second search of PubMed, Embase, Clarivate Analytics/Web of Science Core Collection, ClinicalTrials.gov, and the Wiley/Cochrane Library will follow. Two independent reviewers will perform title and abstract screening, retrieve and review full-text studies, and extract data. The reference lists of all included sources will be screened for additional CHI's or relevant publications about a specific CHI. Data charting will be utilised based on study characteristics and intervention complexity. A 39-item instrument will be used to explore the details in the description of the CHI's development, evaluation, and implementation. The results will be presented in tables, visual outputs, and a narrative summary in response to the review questions.
The proposed review will generate evidence which may provide a direction for the future design of studies on CHI's to prevent ECC and more complete information for those who want to adopt successful interventions to prevent ECC.
本范围综述旨在确定预防幼儿龋病（ECC）的复杂健康干预措施（CHI），探索所确定的 CHI 的复杂性水平，并探索其开发、评估和实施的详细信息。
许多预防 ECC 的干预措施都有多个相互作用的组成部分，可以被视为 CHI。最近对这些干预措施的综述发现效果不确定，这可能是由于 CHI 的开发、评估和实施存在差异。
本范围综述将考虑报告预防 ECC 的 CHI 的临床试验，这些 CHI 始于妊娠期间或生命的第一年。纳入研究的语言为英语，无论其来源国、社会文化背景或背景如何。
本综述将遵循 Joanna Briggs 研究所的范围综述方法。最初在 PubMed 中搜索关键词和医学主题词。随后将在 PubMed、Embase、Clarivate Analytics/Web of Science Core Collection、ClinicalTrials.gov 和 Wiley/Cochrane Library 中进行第二次搜索。两名独立的审查员将进行标题和摘要筛选、检索和审查全文研究，并提取数据。将筛选所有纳入来源的参考文献列表，以获取其他 CHI 或关于特定 CHI 的相关出版物。将根据研究特征和干预措施的复杂性使用数据图表。将使用 39 项工具来探索 CHI 开发、评估和实施的详细描述。结果将以表格、可视化输出和对综述问题的叙述性总结呈现。
拟议的综述将生成证据，这可能为未来预防 ECC 的 CHI 研究设计提供方向，并为那些希望采用成功的预防 ECC 干预措施的人提供更完整的信息。
