From the Department of Nuclear Medicine, Changhai Hospital, Navy Medical University, Shanghai, China.
Clin Nucl Med. 2022 Nov 1;47(11):980-981. doi: 10.1097/RLU.0000000000004269. Epub 2022 May 12.
We describe 68 Ga-FAPI (fibroblast activation protein inhibitor)-04 and 18 F-FDG PET/CT findings in a case with epithelioid malignant pleural mesothelioma. Compared with 18 F-FDG PET/CT, 68 Ga-FAPI-04 PET/CT more clearly showed the pleural tumors and lymph node metastases and detected more pleural lesions because the tumors showed higher 68 Ga-FAPI-04 activity. This case indicates that 68 Ga-FAPI-04 PET/CT may be a promising new tool in evaluation of malignant pleural mesothelioma, which needs further investigation.
我们描述了一例上皮样恶性胸膜间皮瘤患者的 68Ga-FAPI（成纤维细胞激活蛋白抑制剂）-04 和 18F-FDG PET/CT 表现。与 18F-FDG PET/CT 相比，68Ga-FAPI-04 PET/CT 更清楚地显示了胸膜肿瘤和淋巴结转移，并检测到更多的胸膜病变，因为肿瘤显示出更高的 68Ga-FAPI-04 活性。本病例表明，68Ga-FAPI-04 PET/CT 可能是评估恶性胸膜间皮瘤的一种很有前途的新工具，需要进一步研究。
