2021年年中刚果共和国新冠病毒抗体的流行情况。
Prevalence of SARS-CoV-2 antibodies in the Republic of Congo in mid-2021.
作者信息
Niama Fabien R, Koukouikila-Koussounda Félix, Mayengue Pembé Issamou, Elguero Eric, Ngoulou Tarcisse Baloki, Levier Victor, Makran Jamal, Iroungou Berthe A, Aghokeng Avelin F
机构信息
National Laboratory of Public Health, Brazzaville, Republic of Congo.
Marien Ngouabi University, Brazzaville, Republic of Congo.
出版信息
IJID Reg. 2022 Dec;5:121-123. doi: 10.1016/j.ijregi.2022.09.012. Epub 2022 Oct 6.
OBJECTIVES
To estimate the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) antibodies in the general population in the Republic of Congo.
METHODS
In this cross-sectional study, conducted from June to July 2021, participants were recruited from the general population in three districts in the Republic of Congo. Eligible participants were tested for anti-SARS-CoV-2 antibodies using a rapid diagnostic assay.
RESULTS
Overall, 31.8% [95% confidence interval (CI) 29.5-34.0] of the 1669 participants tested positive for anti-SARS-CoV-2 antibodies. Higher prevalence was observed in the rural region (37.3%, 95% CI 31.0-44.1%) than the urban region (30.9%, 95% CI 28.5-33.3); however, the difference was not significant. The risk of testing positive for anti-SARS-CoV-2 antibodies increased significantly with age, ranging from 22.5% (95% CI 18.1-27.5) in 15-24 year olds to 47.9% (95% CI 39.3-56.5) in 55-64 year olds.
CONCLUSIONS
The antibody levels observed in this survey correlate with a moderate rate of virus circulation, which correlates with the low number of confirmed cases of coronavirus disease 2019 in the Republic of Congo.
目的
评估刚果共和国普通人群中严重急性呼吸综合征冠状病毒2（SARS-CoV-2）抗体的血清流行率。
方法
在这项于2021年6月至7月进行的横断面研究中，参与者从刚果共和国三个地区的普通人群中招募。符合条件的参与者使用快速诊断检测法检测抗SARS-CoV-2抗体。
结果
总体而言，1669名参与者中31.8%[95%置信区间（CI）29.5 - 34.0]的抗SARS-CoV-2抗体检测呈阳性。农村地区的流行率（37.3%，95%CI 31.0 - 44.1%）高于城市地区（30.9%，95%CI 28.5 - 33.3）；然而，差异不显著。抗SARS-CoV-2抗体检测呈阳性的风险随年龄显著增加，15 - 24岁人群中为22.5%（95%CI 18.1 - 27.5），55 - 64岁人群中为47.9%（95%CI 39.3 - 56.5）。
结论
本次调查中观察到的抗体水平与病毒的中等传播率相关，这与刚果共和国2019冠状病毒病确诊病例数较少相关。
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